Adiponectin Receptor 1 anticorps

N° du produit ABIN290045

Détail du produit anti-Adiponectin Receptor 1 anticorps

Antigène: Adiponectin Receptor 1 (ADIPOR1)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Adiponectin Receptor 1 est non-conjugé

Application: Western Blotting (WB)

Purification: This antibody was prepared from the serum of a rabbit immunized with a partial peptide representing the N-terminal domain of Human AdipoR1, and purified bypeptide affinity chromatography.

Immunogène: Partial peptide of Human AdipoR1

Information d'application

Indications d'application: Working dilution For Western blotting: 1.0ug/ml

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur Adiponectin Receptor 1

Antigène: Adiponectin Receptor 1 (ADIPOR1)

Autre désignation: AdipoR1 (ADIPOR1 Produits)

Synonymes: anticorps ADIPOR1, anticorps adipor1, anticorps zgc:92893, anticorps ACDCR1, anticorps CGI45, anticorps PAQR1, anticorps TESBP1A, anticorps 2810031L11Rik, anticorps CGI-45, anticorps Paqr1, anticorps zgc:55386, anticorps wu:fj02d08, anticorps acdcr1, anticorps cgi-45, anticorps cgi45, anticorps paqr1, anticorps tesbp1a, anticorps MGC53458, anticorps Adipor1, anticorps adiponectin receptor 1, anticorps adiponectin receptor 1a, anticorps adiponectin receptor 1b, anticorps adiponectin receptor 1 S homeolog, anticorps adiponectin receptor 1 L homeolog, anticorps ADIPOR1, anticorps adipor1a, anticorps Adipor1, anticorps adipor1b, anticorps adipor1, anticorps adipor1.S, anticorps adipor1.L

Sujet: Obesity is a common etiology of diabetes mellitus and other diseases. Certain adipocytokines areconsidered beneficial due to their ability to enhance insulin sensitivity, while others, considereddetrimental, enhance insulin resistance.The beneficial adipocytokine adiponectin displays both anti-diabetic and anti-arteriosclerotic effects. Two distinct adiponectin receptors have been identified. Both AdipoR1 and AdipoR2 are seven-passtransmembrane receptors but are structurally, topologically, and functionally distinct from G-proteincoupled receptors (GPCR) (Ref.1). AdipoR1 is most abundant in muscle whereas AdipoR2 is mostabundant in liver. Both receptors promote fatty acid oxidation and glucose uptake by AMP-activatedprotein kinase and PPAR gamma.PPAR agonists are reported to increase expression of activated adiponectin. PPAR gamma agonists also increase expression of adiponectin receptors (Ref.2). Such findings have focused attention on the role of AdipoR1 in PPAR agonist development.

Pathways: AMPK Signaling