O3FAR1 anticorps

N° du produit ABIN290065

Détail du produit anti-O3FAR1 anticorps

Antigène: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp O3FAR1 est non-conjugé

Application: Flow Cytometry (FACS)

Purification: Protein G

Immunogène: Partial peptide of Human GPR120

Clone: 2B6

Isotype: IgG2a kappa

Information d'application

Indications d'application: WB Not tested. IHC Not tested. ICC Not tested. ELISA Not tested. FCM 1.0-5.0 ug/ml. Neutralization Not tested. IP Not tested

Restrictions: For Research Use only

Stockage

Concentration: 0.25 mg/ml

Buffer: PBS (containing 2% Block Ace as a stabilizer, 0.1% Proclin as a bacteriostat)

Agent conservateur: ProClin

Stock: -20 °C

Détails sur O3FAR1

Antigène: O3FAR1 (omega-3 Fatty Acid Receptor 1 (O3FAR1))

Autre désignation: GPR120 (O3FAR1 Produits)

Synonymes: anticorps BMIQ10, anticorps GPR120, anticorps GPR129, anticorps GT01, anticorps O3FAR1, anticorps PGR4, anticorps AI552415, anticorps Gpr120, anticorps Gpr129, anticorps KPG_013, anticorps O3far1, anticorps Pgr4, anticorps free fatty acid receptor 4, anticorps phosphodiesterase 6C, anticorps FFAR4, anticorps Ffar4, anticorps PDE6C

Sujet: GPR120 is a member of G protein-coupled receptor (GPCR) family and functions as a specific receptor for unsaturated long-chain free fatty acids (FFAs) such aspalmitoleic acid, alpha-linolenic acid, docosahexaenoic acid. The expression of GPR120 is widely detected in various tissues, and GPR120 is highly expressed in th epituitary, lung, small intestine, colon, and adipose tissues.It has been shown that the stimulation of GPR120 by FFAs promotes the secretion of GLP-1, known as the most potent insulinotropic incretin, from the gastrointestinal tract. It has been also demonstrated that FFAs stimulate the ERK and PI3K-Akt pathways through GPR120 and lead to anti-apoptotic effect in enteroendocrine cell line, and that GPR120 regulates adipogenic process such as adipocyte development and differentiation. In addition, a study suggested that GPR120 is expressed in the taste bud cells in circumvallate papillae to sense dietary fat.This antibody is specific to GPR120 and will be useful for research on diabetes, obesity.

Pathways: Hormone Transport