Mre11 anticorps (AA 182-582)

N° du produit ABIN297652

Cet anticorps Souris Monoclonal détecte spécifiquement Mre11 dans WB et IHC. Il présente une réactivité envers Humain.

Aperçu rapide pour Mre11 anticorps (AA 182-582) (ABIN297652)

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp Mre11 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC)

Clone: 4H9

Détail du produit anti-Mre11 anticorps

Épitope: AA 182-582

Specificité: Human Mre11, an 80 kD protein that acts as a Mn+2- dependent double stranded DNA 3' to 5' exonuclease and a single stranded DNA endonuclease. It is part of a larger complex with Rad50, p95 (Nibrin), and possibly other proteins involved in the nucleolytic end-processing of double strand breaks and telomere maintenance

Purification: Protein G purified

Immunogène: GST fusion protein corresponding to aa 182-582 of Mre11 expressed in E. coli.

Type of Immunogen: Fusion protein

Isotype: IgG1

Information d'application

Indications d'application: Optimal working dilution should be determined by the investigator.

Commentaires:

Target Species of Antibody: Human

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: Lot specific

Buffer: PBS, 0.01 % sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: 4 °C,-20 °C

Stockage commentaire: Short term: 4°C. Long term: Store at -20°C. Avoid freeze-thaw cycles.

Détails sur Mre11

Antigène: Mre11 (MRE11A) (MRE11 Meiotic Recombination 11 Homolog A (S. Cerevisiae) (MRE11A))

Autre désignation: MRE11A / MRE11

Sujet: Name/Gene ID: MRE11A

Synonyms: MRE11A, AT-like disease, Endo/exonuclease Mre11, HNGS1, MRE11, MRE11 homolog 1, MRE11 homolog A, MRE11B, ATLD

ID gène: 4361

UniProt: P49959

Pathways: Réparation de l'ADN