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PLVAP anticorps (Biotin)

PLVAP Reactivité: Souris FACS, IHC, IHC (fro) Hôte: Rat Monoclonal MECA-32 Biotin
N° du produit ABIN298900
  • Antigène Voir toutes PLVAP Anticorps
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Reactivité
    • 28
    • 6
    • 1
    Souris
    Hôte
    • 21
    • 7
    • 4
    Rat
    Clonalité
    • 22
    • 9
    Monoclonal
    Conjugué
    • 19
    • 5
    • 2
    • 2
    • 2
    • 2
    Cet anticorp PLVAP est conjugé à/à la Biotin
    Application
    • 30
    • 21
    • 16
    • 8
    • 6
    • 5
    • 4
    • 4
    • 1
    • 1
    • 1
    Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Specificité
    Recognizes murine plasmalemma vesicle-associated protein (PLVAP), a 60kD protein which is otherwise known as MECA-32 and PV-1. PLVAP is a transmembrane homodimer which is associated with endothelial cell caveolae and fenestrae. In adult and embryonic mice, PLVAP is primarily expressed on endothelial tissues but shows restricted distribution in the skeletal, cardiac and brain tissues. In embryonic mice, PLVAP expression, on the vasculature associated with blood brain barrier has been reported to be developmentally regulated. In humans, PLVAP is selectively up-regulated in a variety of high-grade brain tumors, including glioblastoma and metastatic carcinoma, as well as other cerebral disorders associated with blood-brain barrier disruption, such as acute ischemia. PLVAP represents a novel marker of brain tumor angiogenesis and integrity of the blood-brain barrier and is a potential therapeutic target.
    Purification
    Affinity purified
    Immunogène


    Type of Immunogen: Native protein
    Clone
    MECA-32
    Isotype
    IgG2a
    Top Product
    Discover our top product PLVAP Anticorps primaire
  • Indications d'application
    Approved: Flo, IHC, IHC-Fr (1:1 - 1:10)

    Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested. Flow Cytometry: Use 10 μL of the suggested working dilution to label 1x10^6 cells in 100 μL. Method sheets are available on request.
    Commentaires

    Target Species of Antibody: Mouse

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    PBS,  pH 7.4, 0.09 % sodium azide, 1 % BSA.
    Agent conservateur
    Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Stock
    -20 °C
    Stockage commentaire
    Short term: -20°C
    Long term: -20°C.
  • Antigène
    PLVAP (Plasmalemma Vesicle Associated Protein (PLVAP))
    Autre désignation
    PV1 / PLVAP (PLVAP Produits)
    Synonymes
    anticorps MECA32, anticorps Pv1, anticorps FELS, anticorps PV-1, anticorps PV1, anticorps gp68, anticorps plasmalemma vesicle associated protein, anticorps Plvap, anticorps PLVAP
    Sujet
    Name/Gene ID: PLVAP

    Synonyms: PLVAP, gp68, FELS, Plasmalemma vesicle protein 1, PV-1, PV1
    ID gène
    83483
    UniProt
    Q9BX97
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