Thrombopoietin anticorps (AA 22-349)

N° du produit ABIN3015586

Détail du produit anti-Thrombopoietin anticorps

Antigène: Thrombopoietin (THPO)

Épitope: AA 22-349

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Thrombopoietin est non-conjugé

Application: Western Blotting (WB)

Séquence: SPAPPACDLR VLSKLLRDSH VLHSRLSQCP EVHPLPTPVL LPAVDFSLGE WKTQMEETKA QDILGAVTLL LEGVMAARGQ LGPTCLSSLL GQLSGQVRLL LGALQSLLGT QGRTTAHKDP NAIFLSFQHL LRGKVRFLML VGGSTLCVRR APPTTAVPSR TSLVLTLNEL PNRTSGLLET NFTASARTTG SGLLKWQQGF RAKIPGLLNQ TSRSLDQIPG YLNRIHELLN GTRGLFPGPS RRTLGAPDIS SGTSDTGSLP PNLQPGYSPS PTHPPTGQYT LFPLPPTLPT PVVQLHPLLP DPSAPTPTPT SPLLNTSYTH SQNLSQEG

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 22-349 of human THPO (NP_001171068.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Thrombopoietin

Antigène: Thrombopoietin (THPO)

Autre désignation: THPO (THPO Produits)

Synonymes: anticorps MGDF, anticorps MKCSF, anticorps ML, anticorps MPLLG, anticorps THCYT1, anticorps TPO, anticorps Mgdf, anticorps Ml, anticorps Mpllg, anticorps Tpo, anticorps Tpo1, anticorps Tpo2, anticorps Tpo3, anticorps Tpo4, anticorps tpo, anticorps LOC100231762, anticorps thrombopoietin, anticorps THPO, anticorps Thpo, anticorps thpo

Sujet: Megakaryocytopoiesis is the cellular development process that leads to platelet production. The main functional protein encoded by this gene is a humoral growth factor that is necessary for megakaryocyte proliferation and maturation, as well as for thrombopoiesis. This protein is the ligand for MLP/C_MPL, the product of myeloproliferative leukemia virus oncogene. Mutations in this gene are the cause of thrombocythemia 1. Alternative promoter usage and differential splicing result in multiple transcript variants differing in the 5' UTR and/or coding region. Multiple AUG codons upstream of the main open reading frame (ORF) have been identified, and these upstream AUGs inhibit translation of the main ORF at different extent.,THPO,MGDF,MKCSF,ML,MPLLG,THCYT1,TPO,Cancer,Cell Biology & Developmental Biology,Cell Cycle,Cell differentiation,Growth factor,Immunology & Inflammation,Cytokines,Stem Cells,Mesenchymal Stem Cells,Cardiovascular,Blood,THPO

Poids moléculaire: 33 kDa/37 kDa

ID gène: 7066

UniProt: P40225

Pathways: Signalistation JAK/STAT, Hormone Activity