MEK1 anticorps (pSer221, Ser217, Ser221)
Aperçu rapide pour MEK1 anticorps (pSer221, Ser217, Ser221) (ABIN3019812)
Antigène
Voir toutes MEK1 (MAP2K1) AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- pSer221, Ser217, Ser221
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Réactivité croisée
- Humain, Souris, Rat
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Attributs du produit
- Phosphorylated Antibodies
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Immunogène
- A phospho specific peptide corresponding to residues surrounding serine 217/221 of human MAP2K1/MAP2K2.
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Isotype
- IgG
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Indications d'application
- WB,1:500 - 1:1000
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Restrictions
- For Research Use only
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Agent conservateur
- Sodium azide
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Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Stock
- -20 °C
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Stockage commentaire
- Store at -20°C. Avoid freeze / thaw cycles.
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- MEK1 (MAP2K1) (Mitogen-Activated Protein Kinase Kinase 1 (MAP2K1))
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Autre désignation
- MAP2K1/MAP2K2
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Sujet
- The protein encoded by this gene is a member of the dual specificity protein kinase family, which acts as a mitogen-activated protein (MAP) kinase kinase. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act as an integration point for multiple biochemical signals. This protein kinase lies upstream of MAP kinases and stimulates the enzymatic activity of MAP kinases upon wide variety of extra- and intracellular signals. As an essential component of MAP kinase signal transduction pathway, this kinase is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development. [provided by RefSeq, Jul 2008],MEK1/MEK2,Protein phosphorylation,Protein phosphorylation,Protein phosphorylation,MAP2K1/MAP2K2
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Poids moléculaire
- 40 kDa/43 kDa/44 kDa
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ID gène
- 5604, 5605
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UniProt
- Q02750, P36507
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Pathways
- Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Activation of Innate immune Response, Toll-Like Receptors Cascades, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, BCR Signaling
Antigène
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