ERK1 anticorps (AA 1-100)

N° du produit ABIN3020725

Il existe 8+ publications pour ce produit. L’anticorps anti-ERK1 Polyclonal Lapin est utilisé pour la détection de ERK1 dans des échantillons de Humain. Il a été validé pour WB, IHC et IF.

Aperçu rapide pour ERK1 anticorps (AA 1-100) (ABIN3020725)

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ERK1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-ERK1 anticorps

Épitope: AA 1-100

Séquence: MAAAAAQGGG GGEPRRTEGV GPGVPGEVEM VKGQPFDVGP RYTQLQYIGE GAYGMVSSAY DHVRKTRVAI KKISPFEHQT YCQRTLREIQ ILLRFRHENV

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 1-100 of human ERK1 (NP_002737.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Références pour anticorps anti-ERK1 (ABIN3020725)

He, Zhao, Anees, Li, Ashraf, Chen, Song, Chen, Cao, Ye: "p21-Activated Kinase 4 Signaling Promotes Japanese Encephalitis Virus-Mediated Inflammation in Astrocytes." dans: Frontiers in cellular and infection microbiology, Vol. 7, pp. 271, (2018) (PubMed).

Zhu, Ye, Ashraf, Li, Chen, Song, Cao: "Transcriptional regulation of miR-15b by c-Rel and CREB in Japanese encephalitis virus infection." dans: Scientific reports, Vol. 6, pp. 22581, (2017) (PubMed).

Li, Fan, Gao, Fan, Liu: "Effect of Fructus Ligustri Lucidi on osteoblastic like cell-line MC3T3-E1." dans: Journal of ethnopharmacology, Vol. 170, pp. 88-95, (2016) (PubMed).

Wu, Qin, Guo, Li, Chen: "AKT/ERK activation is associated with gastric cancer cell resistance to paclitaxel." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 4, pp. 1449-58, (2015) (PubMed).

Fan, Zhang, Hu, Li, Zhang: "Activation of AKT/ERK confers non-small cell lung cancer cells resistance to vinorelbine." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 1, pp. 134-43, (2014) (PubMed).

Feng, Yu, Liu, Zhang, Cheng, Li, Tan, Luo, Jiang: "KAT5 silencing induces apoptosis of GBC-SD cells through p38MAPK-mediated upregulation of cleaved Casp9." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 1, pp. 80-91, (2014) (PubMed).

Li, Wang, Pan, Wang, Fan, Sun: "RNAi screening with shRNAs against histone methylation-related genes reveals determinants of sorafenib sensitivity in hepatocellular carcinoma cells." dans: International journal of clinical and experimental pathology, Vol. 7, Issue 3, pp. 1085-92, (2014) (PubMed).

Xu, Hang, Hu, Gao: "RAF1-MEK1-ERK/AKT axis may confer NSCLC cell lines resistance to erlotinib." dans: International journal of clinical and experimental pathology, Vol. 6, Issue 8, pp. 1493-504, (2013) (PubMed).

Détails sur ERK1

Antigène: ERK1 (MAPK3) (Mitogen-Activated Protein Kinase 3 (MAPK3))

Autre désignation: MAPK3

Sujet: The protein encoded by this gene is a member of the MAP kinase family. MAP kinases, also known as extracellular signal-regulated kinases (ERKs), act in a signaling cascade that regulates various cellular processes such as proliferation, differentiation, and cell cycle progression in response to a variety of extracellular signals. This kinase is activated by upstream kinases, resulting in its translocation to the nucleus where it phosphorylates nuclear targets. Alternatively spliced transcript variants encoding different protein isoforms have been described.,ERK-1,ERK1,ERT2,HS44KDAP,HUMKER1A,P44ERK1,P44MAPK,PRKM3,p44-ERK1,p44-MAPK,MAPK3,Epigenetics & Nuclear Signaling,Translation Control,Regulation of eIF4 and p70 S6 Kinase,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Kinase,Serine/threonine kinases,mTOR Signaling Pathway,ErbB-HER Signaling Pathway,MAPK-Erk Signaling Pathway,Cell Biology & Developmental Biology,Apoptosis,Mitochondrial Control of Apoptosis,Inhibition of Apoptosis,Cell Cycle,Centromere,Microtubules,TGF-b-Smad Signaling Pathway,ESC Pluripotency and Differentiation,Endocrine & Metabolism,Insulin Receptor Signaling Pathway,Warburg Effect,Immunology & Inflammation,B Cell Receptor Signaling Pathway,T Cell Receptor Signaling Pathway,IL-6 Receptor Signaling Pathway,Neuroscience,Neurodegenerative Diseases,Amyloid Plaque and Neurofibrillary Tangle Formation in Alzheimer's Disease,Stem Cells,Cardiovascular,Angiogenesis,MAPK3

Poids moléculaire: 38 kDa/40 kDa/43 kDa

ID gène: 5595

UniProt: P27361

Pathways: Signalisation MAPK, Signalisation RTK, Interferon-gamma Pathway, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, Response to Growth Hormone Stimulus, Activation of Innate immune Response, Cellular Response to Molecule of Bacterial Origin, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Signaling Events mediated by VEGFR1 and VEGFR2, Signaling of Hepatocyte Growth Factor Receptor, VEGFR1 Specific Signals, S100 Proteins