Pro-Glucagon (AA 21-180) anticorps

N° du produit ABIN3021471

Détail du produit

Antigène: Pro-Glucagon

Épitope: AA 21-180

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Application: Immunofluorescence (IF), Immunohistochemistry (IHC)

Séquence: RSLQDTEEKS RSFSASQADP LSDPDQMNED KRHSQGTFTS DYSKYLDSRR AQDFVQWLMN TKRNRNNIAK RHDEFERHAE GTFTSDVSSY LEGQAAKEFI AWLVKGRGRR DFPEEVAIVE ELGRRHADGS FSDEMNTILD NLAARDFINW LIQTKITDRK

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 21-180 of human Pro-glucagon (NP_002045.1).

Isotype: IgG

Information d'application

Indications d'application: IHC,1:100 - 1:200,IF,1:100 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détail du antigène

Antigène: Pro-Glucagon

Sujet: The protein encoded by this gene is actually a preproprotein that is cleaved into four distinct mature peptides. One of these, glucagon, is a pancreatic hormone that counteracts the glucose-lowering action of insulin by stimulating glycogenolysis and gluconeogenesis. Glucagon is a ligand for a specific G-protein linked receptor whose signalling pathway controls cell proliferation. Two of the other peptides are secreted from gut endocrine cells and promote nutrient absorption through distinct mechanisms. Finally, the fourth peptide is similar to glicentin, an active enteroglucagon.,GCG,GLP-1,GLP1,GLP2,GRPP,glucagon,Cancer,Signal Transduction,Endocrine & Metabolism,Endocrine and metabolic diseases,Diabetes,Neuroscience,Stem Cells,Cardiovascular,Heart,Cardiovascular diseases,Heart disease,Pro-glucagon

Poids moléculaire: 20 kDa

ID gène: 2641

UniProt: P01275