DcR1 anticorps (AA 30-130)

N° du produit ABIN3021518

Détail du produit anti-DcR1 anticorps

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Épitope: AA 30-130

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp DcR1 est non-conjugé

Application: Western Blotting (WB)

Séquence: RQEEVPQQTV APQQQRHSFK GEECPAGSHR SEHTGACNPC TEGVDYTNAS NNEPSCFPCT VCKSDQKHKS SCTMTRDTVC QCKEGTFRNE NSPEMCRKCS R

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human TNFRSF10C (NP_003832.2).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur DcR1

Antigène: DcR1 (TNFRSF10C) (Tumor Necrosis Factor Receptor Superfamily, Member 10c (TNFRSF10C))

Autre désignation: TNFRSF10C (TNFRSF10C Produits)

Synonymes: anticorps CD263, anticorps DCR1, anticorps DCR1-TNFR, anticorps LIT, anticorps TRAIL-R3, anticorps TRAILR3, anticorps TRID, anticorps TNFRSF10C, anticorps TNF receptor superfamily member 10c, anticorps TNFRSF10C

Sujet: The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contains an extracellular TRAIL-binding domain and a transmembrane domain, but no cytoplasmic death domain. This receptor is not capable of inducing apoptosis, and is thought to function as an antagonistic receptor that protects cells from TRAIL-induced apoptosis. This gene was found to be a p53-regulated DNA damage-inducible gene. The expression of this gene was detected in many normal tissues but not in most cancer cell lines, which may explain the specific sensitivity of cancer cells to the apoptosis-inducing activity of TRAIL.,TNFRSF10C,CD263,DCR1,DCR1-TNFR,LIT,TRAIL-R3,TRAILR3,TRID,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,Cytokines,NF-kB Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TNFRSF10C

Poids moléculaire: 27 kDa

ID gène: 8794

UniProt: O14798

Pathways: Apoptose