Arrestin 3 anticorps (AA 300-400)

N° du produit ABIN3021620

Cet anticorps anti-Arrestin 3 est un anticorps Lapin Polyclonal détectant Arrestin 3 dans WB, IHC et IF. Adapté pour Humain.

Aperçu rapide pour Arrestin 3 anticorps (AA 300-400) (ABIN3021620)

Antigène: Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Arrestin 3 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)

Détail du produit anti-Arrestin 3 anticorps

Épitope: AA 300-400

Séquence: NLASSTIVKE GANKEVLGIL VSYRVKVKLV VSRGGDVSVE LPFVLMHPKP HDHIPLPRPQ SAAPETDVPV DTNLIEFDTN YATDDDIVFE DFARLRLKGM K

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: A synthetic peptide corresponding to a sequence within amino acids 300-400 of human ARRB2 (NP_004304.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IF,1:50 - 1:200

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur Arrestin 3

Antigène: Arrestin 3 (ARRB2) (Arrestin, beta 2 (ARRB2))

Autre désignation: ARRB2

Sujet: Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. Arrestin beta 2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for arrestin beta 2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.,ARRB2,ARB2,ARR2,BARR2,Signal Transduction,G protein signaling,G2/M DNA Damage Checkpoint,Cell Biology & Developmental Biology,Hedgehog Signaling Pathway,Notch Signaling Pathway,ARRB2

Poids moléculaire: 44 kDa/45 kDa/46 kDa/47 kDa/48 kDa

ID gène: 409

UniProt: P32121

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Regulation of Intracellular Steroid Hormone Receptor Signaling, cAMP Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Synaptic Membrane, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Phototransduction, Thromboxane A2 Receptor Signaling