CD3 epsilon anticorps (AA 25-207)

N° du produit ABIN3022492

Cet anticorps Lapin Polyclonal détecte spécifiquement CD3 epsilon dans WB, IHC et IP. Il présente une réactivité envers Humain.

Aperçu rapide pour CD3 epsilon anticorps (AA 25-207) (ABIN3022492)

Antigène: CD3 epsilon (CD3E)

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CD3 epsilon est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP)

Détail du produit anti-CD3 epsilon anticorps

Épitope: AA 25-207

Séquence: NEEMGGITQT PYKVSISGTT VILTCPQYPG SEILWQHNDK NIGGDEDDKN IGSDEDHLSL KEFSELEQSG YYVCYPRGSK PEDANFYLYL RARVCENCME MDVMSVATIV IVDICITGGL LLLVYYWSKN RKAKAKPVTR GAGAGGRQRG QNKERPPPVP NPDYEPIRKG QRDLYSGLNQ RRI

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Purification: Affinity purification

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 25-207 of human CD3E (NP_000724.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000,IHC,1:50 - 1:200,IP,1:50 - 1:100

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur CD3 epsilon

Antigène: CD3 epsilon (CD3E)

Autre désignation: CD3E

Sujet: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.,CD3E,IMD18,T3E,TCRE,CD3e molecule,Cell Biology & Developmental Biology,Apoptosis,Immunology & Inflammation,CD markers,T Cell Receptor Signaling Pathway,Stem Cells,Hematopoietic Progenitors,CD3E

Poids moléculaire: 23 kDa

ID gène: 916

UniProt: P07766

Pathways: TCR Signaling, CXCR4-mediated Signaling Events, Ubiquitin Proteasome Pathway