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TIRAP anticorps (AA 1-221)
TIRAP
Reactivité: Humain
IHC
Hôte: Lapin
Polyclonal
unconjugated
N° du produit ABIN3022678
Détail du produit anti-TIRAP anticorps
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Antigène
Voir toutes TIRAP Anticorps
TIRAP
(Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
Épitope
Tous les épitopes à travers TIRAP Anticorps.
AA 1-221
Reactivité
Toutes les réactivités sur TIRAP Anticorps
Humain
Hôte
Toutes les hôtes sur TIRAP Anticorps
Lapin
Clonalité
Toutes les clonalités sur TIRAP Anticorps
Polyclonal
Conjugué
Tous les conjugués à travers TIRAP Anticorps
Cet anticorp TIRAP est non-conjugé
Application
Tous les applications à travers TIRAP Anticorps.
Immunohistochemistry (IHC)
Séquence
MASSTSLPAP GSRPKKPLGK MADWFRQTLL KKPKKRPNSP ESTSSDASQP TSQDSPLPPS LSSVTSPSLP PTHASDSGSS RWSKDYDVCV CHSEEDLVAA QDLVSYLEGS TASLRCFLQL RDATPGGAIV SELCQALSSS HCRVLLITPG FLQDPWCKYQ MLQALTEAPG AEGCTIPLLS GLSRAAYPPE LRFMYYVDGR GPDGGFRQVK EAVMRYLQTL S
Réactivité croisée
Humain
Attributs du produit
Polyclonal Antibodies
Immunogène
Recombinant fusion protein containing a sequence corresponding to amino acids 1-221 of human TIRAP (NP_001034750.1).
Isotype
IgG
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Alternatives
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Information d'application
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Indications d'application
IHC,1:50 - 1:200
Restrictions
For Research Use only
Stockage
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Buffer
PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
Agent conservateur
Sodium azide
Précaution d'utilisation
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Stock
-20 °C
Stockage commentaire
Store at -20°C. Avoid freeze / thaw cycles.
Détails sur TIRAP
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Antigène
TIRAP
(Toll-Interleukin 1 Receptor (TIR) Domain Containing Adaptor Protein (TIRAP))
Autre désignation
TIRAP (TIRAP Produits )
Synonymes
anticorps mal, anticorps wyatt, anticorps BACTS1, anticorps Mal, anticorps MyD88-2, anticorps AA407980, anticorps C130027E04Rik, anticorps Tlr4ap, anticorps Wyatt, anticorps toll-interleukin 1 receptor (TIR) domain containing adaptor protein, anticorps TIR domain containing adaptor protein, anticorps toll-interleukin 1 receptor (TIR) domain containing adaptor protein L homeolog, anticorps toll-interleukin 1 receptor (TIR) domain-containing adaptor protein, anticorps tirap, anticorps TIRAP, anticorps tirap.L, anticorps Tirap
Sujet
The innate immune system recognizes microbial pathogens through Toll-like receptors (TLRs), which identify pathogen-associated molecular patterns. Different TLRs recognize different pathogen-associated molecular patterns and all TLRs have a Toll-interleukin 1 receptor (TIR) domain, which is responsible for signal transduction. The protein encoded by this gene is a TIR adaptor protein involved in the TLR4 signaling pathway of the immune system. It activates NF-kappa-B, MAPK1, MAPK3 and JNK, which then results in cytokine secretion and the inflammatory response. Alternative splicing of this gene results in several transcript variants, however, not all variants have been fully described.,TIRAP,BACTS1,Mal,MyD88-2,wyatt,Signal Transduction,Kinase,Immunology & Inflammation,Toll-like Receptor Signaling Pathway,Cell Intrinsic Innate Immunity Signaling Pathway,TLR Signaling,Cardiovascular,TIRAP
Poids moléculaire
23 kDa/25 kDa/27 kDa
ID gène
114609
UniProt
P58753
Pathways
Signalisation TLR , Activation of Innate immune Response , Cellular Response to Molecule of Bacterial Origin , Toll-Like Receptors Cascades
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