KCNQ1 anticorps (AA 250-549)

N° du produit ABIN3023121

Détail du produit anti-KCNQ1 anticorps

Antigène: KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))

Épitope: AA 250-549

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNQ1 est non-conjugé

Application: Western Blotting (WB)

Séquence: TAWRCYAAEN PDSSTWKIYI RKAPRSHTLL SPSPKPKKSV VVKKKKFKLD KDNGVTPGEK MLTVPHITCD PPEERRLDHF SVDGYDSSVR KSPTLLEVSM PHFMRTNSFA EDLDLEGETL LTPITHISQL REHHRATIKV IRRMQYFVAK KKFQQARKPY DVRDVIEQYS QGHLNLMVRI KELQRRLDQS IGKPSLFISV SEKSKDRGSN TIGARLNRVE DKVTQLDQRL ALITDMLHQL LSLHGGSTPG SGGPPREGGA HITQPCGSGG SVDPELFLPS NTLPTYEQLT VPRRGPDEGS

Réactivité croisée: Humain, Souris, Rat

Attributs du produit: Polyclonal Antibodies

Immunogène: Recombinant fusion protein containing a sequence corresponding to amino acids 250-549 of human KCNQ1 (NP_861463.1).

Isotype: IgG

Information d'application

Indications d'application: WB,1:500 - 1:2000

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid freeze / thaw cycles

Stock: -20 °C

Stockage commentaire: Store at -20°C. Avoid freeze / thaw cycles.

Détails sur KCNQ1

Antigène: KCNQ1 (Potassium Voltage-Gated Channel, KQT-Like Subfamily, Member 1 (KCNQ1))

Autre désignation: KCNQ1 (KCNQ1 Produits)

Synonymes: anticorps ATFB1, anticorps ATFB3, anticorps JLNS1, anticorps KCNA8, anticorps KCNA9, anticorps KVLQT1, anticorps Kv1.9, anticorps Kv7.1, anticorps LQT, anticorps LQT1, anticorps RWS, anticorps SQT2, anticorps WRS, anticorps CG12215, anticorps CG12915, anticorps CG33135, anticorps DKCNQ, anticorps Dmel\\CG33135, anticorps dKCNQ, anticorps kcnq1, anticorps KCNQ1, anticorps kqt-3, anticorps kv7.1, anticorps Kvlqt1, anticorps KvLQT-1, anticorps kcnq1-A, anticorps xkvlqt1, anticorps zgc:158384, anticorps AW559127, anticorps Kcna9, anticorps KvLQT1, anticorps potassium voltage-gated channel subfamily Q member 1, anticorps KCNQ potassium channel, anticorps potassium voltage-gated channel, KQT-like subfamily, member 1, anticorps potassium channel, voltage gated KQT-like subfamily Q, member 1, anticorps voltage gated potassium channel subunit, anticorps potassium channel, voltage gated KQT-like subfamily Q, member 1 L homeolog, anticorps potassium voltage-gated channel, subfamily Q, member 1, anticorps KCNQ1, anticorps KCNQ, anticorps kcnq1, anticorps Kcnq1, anticorps kcnq1.L

Sujet: This gene encodes a voltage-gated potassium channel required for repolarization phase of the cardiac action potential. This protein can form heteromultimers with two other potassium channel proteins, KCNE1 and KCNE3. Mutations in this gene are associated with hereditary long QT syndrome 1 (also known as Romano-Ward syndrome), Jervell and Lange-Nielsen syndrome, and familial atrial fibrillation. This gene exhibits tissue-specific imprinting, with preferential expression from the maternal allele in some tissues, and biallelic expression in others. This gene is located in a region of chromosome 11 amongst other imprinted genes that are associated with Beckwith-Wiedemann syndrome (BWS), and itself has been shown to be disrupted by chromosomal rearrangements in patients with BWS. Alternatively spliced transcript variants have been found for this gene.,KCNQ1,ATFB1,ATFB3,JLNS1,KCNA8,KCNA9,KVLQT1,Kv1.9,Kv7.1,LQT,LQT1,RWS,SQT2,WRS,Signal Transduction,Endocrine & Metabolism,Neuroscience,Cardiovascular,Heart,Cardiac arrhythmias,KCNQ1

Poids moléculaire: 61 kDa/74 kDa

ID gène: 3784

UniProt: P51787

Pathways: Negative Regulation of Hormone Secretion, Sensory Perception of Sound