TRIM29 anticorps (N-Term)

N° du produit ABIN3023984

Cet anticorps Souris Monoclonal détecte spécifiquement TRIM29 dans IF et IHC (p). Il présente une réactivité envers Humain.

Aperçu rapide pour TRIM29 anticorps (N-Term) (ABIN3023984)

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp TRIM29 est non-conjugé

Application: Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: TPMP29-1

Détail du produit anti-TRIM29 anticorps

Épitope: N-Term

Purification: Protein G affinity chromatography

Immunogène: An N-terminal human recombinant protein fragment was used as the immunogen for the TRIM29 antibody.

Isotype: IgG2a kappa

Information d'application

Indications d'application: Titering of the TRIM29 antibody may be required for optimal performance.

1. FFPE testing requires sections to be boiled in  pH 6 10  mM citrate buffer for 10-20 minutes, followed by cooling at RT for 20 minutes, prior to staining.
2. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.\. Immunofluorescence: 0.5-1 μg/mL,Immunohistochemistry (FFPE): 0.5-1 μg/mL for 30 min at RT (1),Prediluted format : incubate for 30 min at RT (2)

Restrictions: For Research Use only

Stockage

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the TRIM29 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).

Détails sur TRIM29

Antigène: TRIM29 (Tripartite Motif Containing 29 (TRIM29))

Autre désignation: TRIM29

Sujet: Tripartite motif-containing protein 29 interacts with the intermediate filament protein vimentin, a substrate for the PKC family of protein kinases, and with hPKCI-1, an inhibitor of the PKCs. TRIM29 protein contains both zinc finger and leucine zipper motifs, suggesting that the it may form homodimers and possibly associate with DNA.

Pathways: Signalisation p53, Apoptose, Réparation de l'ADN, Inositol Metabolic Process, Positive Regulation of Response to DNA Damage Stimulus