VWF anticorps
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- Antigène Voir toutes VWF Anticorps
- VWF (Von Willebrand Factor (VWF))
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Reactivité
- Humain
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Hôte
- Souris
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Clonalité
- Monoclonal
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Conjugué
- Cet anticorp VWF est non-conjugé
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Application
- Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Purification
- Protein G purified
- Immunogène
- A recombinant human protein fragment was used as the immunogen for this von Willebrand Factor antibody.
- Clone
- WFA52-2
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product VWF Anticorps primaire
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- Indications d'application
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Variations in protocols, secondaries and substrates may require the von Willebrand Factor antibody to be titered for optimal performance.
1. FFPE staining requires boiling tissue sections in 10 mM Citrate Buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes.\. FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL,WB: 0.5-1.0 μg/mL,IHC (FFPE): 0.5-1.0 μg/mL for 30 minutes at RT (1)
- Restrictions
- For Research Use only
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- Concentration
- 0.2 mg/mL
- Buffer
- 0.2 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide
- Agent conservateur
- Sodium azide
- Précaution d'utilisation
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Stock
- 4 °C,-20 °C
- Stockage commentaire
- Store the von Willebrand Factor antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
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- Antigène
- VWF (Von Willebrand Factor (VWF))
- Autre désignation
- Von Willebrand Factor (VWF Produits)
- Synonymes
- anticorps VWF, anticorps si:ch1073-474e24.1, anticorps F8VWF, anticorps VWD, anticorps 6820430P06Rik, anticorps AI551257, anticorps B130011O06Rik, anticorps C630030D09, anticorps von Willebrand factor, anticorps Von Willebrand factor, anticorps VWF, anticorps vwf, anticorps Vwf
- Sujet
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Von Willebrand Factor (vWF) is a glycoprotein produced by bone marrow cells and endothelial cells lining the inside surface of blood vessels. Its primary function is platelet adhesion, binding to Factor VIII, collagen and platelets, to coagulate blood at the site of wounding. The enzyme VWFCP, or vWF-cleaving protease, facilitates clotting by cutting the protein into subunits, increasing its binding capacity.
Deficiency or dysfunction of the protein increases the tendency of wounds to bleed, or to bleed more. Over 300 gene mutations have been identified and classified into three types. Type 1 von Willebrand Factor disease is characterized by reduced amounts in the bloodstream, Type 2 by reduced binding ability and Type 3 by a nonfunctional protein.
- ID gène
- 7450
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