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CD2 anticorps

CD2 Reactivité: Humain FACS, IF, Func Hôte: Souris Monoclonal 1E7E8-G4 unconjugated

N° du produit ABIN3024308

Fiche de données

Antigène Voir toutes CD2 Anticorps

CD2
Reactivité
158

35

17

15

12

10

8

5

3

3

3

3

2

2

1

1

1

1

1

1
Humain
Hôte
128

44

23

2
Souris
Anticorps secondaires appropriés
Clonalité
151

44

2
Monoclonal
Conjugué
84

22

21

14

8

4

4

4

4

4

4

4

3

3

3

2

1

1

1

1

1

1

1

1

1
Cet anticorp CD2 est non-conjugé
Application
137

52

52

32

32

30

21

11

10

9

3

3

2

1

1

1

1

1

1

1

1
Flow Cytometry (FACS), Immunofluorescence (IF), Functional Studies (Func)

Purification

Protein G affinity chromatography

Immunogène

Human Thymocytes/Sezary T cells were used as the immunogen for this CD2 antibody.

Clone

1E7E8-G4

Isotype

IgG2a kappa

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Indications d'application

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.\. Functional Testing: order azide-free format,FACS: 0.5-1 μg/million cells,IF: 0.5-1 μg/mL

Restrictions

For Research Use only
Concentration

1 mg/mL

Buffer

1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur

Azide free

Stock

4 °C,-20 °C

Stockage commentaire

Store the CD2 antibody at 2-8°C (with azide) or aliquot and store at -20°C or colder (without azide).
Antigène

CD2

Autre désignation

CD2 (CD2 Produits)

Synonymes

anticorps CD2, anticorps LFA-2, anticorps Ly-37, anticorps Ly37, anticorps SRBC, anticorps T11, anticorps CD2R, anticorps LFA2, anticorps OX-34, anticorps OX34, anticorps CD2 molecule, anticorps CD2 antigen, anticorps Cd2 molecule, anticorps CD2, anticorps Cd2

Sujet

CD2 interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on peripheral blood T lymphocytes, NK cells and thymocytes. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium. Interaction between CD2 and its counter receptor LFA3 (CD58) on opposing cells optimizes immune system recognition, thereby facilitating communication between helper T lymphocytes and antigen-presenting cells, as well as between cytolytic effectors and target cells.

ID gène

914