Oxytocin Receptor anticorps (C-Term)

N° du produit ABIN302439

Détail du produit anti-Oxytocin Receptor anticorps

Antigène: Oxytocin Receptor (OXTR)

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Oxytocin Receptor est non-conjugé

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects Oxytocin Receptor (OXTR), C-terminal cytoplasmic domain.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic peptide -KLH conjugated corresponding to C-terminal cytoplasmic domain of Human Oxytocin Receptor (OXTR).

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (40 μg/mL). Antigen retrieval: Steam slides in 0.01M sodium citrate buffer, pH 6.0, at 99-100 °C for 20 min. Remove from heat and let stand at room temperature in buffer for 20 min. Rinse in 1xTBS with Tween (TBST) for 1 min. at room temperature.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline containing 0.09 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C to -70 °C for longer.

Détails sur Oxytocin Receptor

Antigène: Oxytocin Receptor (OXTR)

Autre désignation: Oxytocin Receptor / OXTR (OXTR Produits)

Synonymes: anticorps OXTR, anticorps OT-R, anticorps OTR, anticorps OTR1, anticorps oxytocin receptor, anticorps OXTR, anticorps Oxtr

Sujet: The oxytocin receptor belongs to the vasopressin/oxytocin family of GPCRs because it binds similar cyclic nonapeptide hormones. The oxytocin receptor functions primarily during labor and lactation. There is a dramatic increase in the number of oxytocin receptors just before the onset of labor causing the uterine muscles to become exceedingly sensitive to oxytocin. The activated oxytocin receptor causes an inward membrane current that results in smooth muscle contraction during labor and milk ejection during lactation. This receptor also plays a role in natriuresis, kaliuresis and may have an antistress effect.Synonyms: OT-R

ID gène: 5021

NCBI Accession: NP_000907

UniProt: P30559

Pathways: Myometrial Relaxation and Contraction, Feeding Behaviour