OTUD5 anticorps (C-Term)

N° du produit ABIN3025356

Détail du produit anti-OTUD5 anticorps

Antigène: OTUD5 (OTU Domain Containing 5 (OTUD5))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OTUD5 est non-conjugé

Application: Western Blotting (WB)

Purification: Protein A affinity chromatography

Immunogène: A recombinant protein fragment from the C-terminal region of human OTUD5 was used as the immunogen for this antibody.

Isotype: IgG

Information d'application

Indications d'application: Provided assay concentrations are suggestions only, antibody titration may be required for optimal results.\. Western blot: 2-5 μg/mL

Restrictions: For Research Use only

Stockage

Concentration: 0.5 mg/mL

Buffer: 0.5 mg/mL in 1X PBS with 0.1 mg/mL BSA (US sourced) and 0.05 % sodium azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Stockage commentaire: Aliquot the antibody and store frozen at -20°C or colder. Avoid repeated freeze-thaw cycles.

Détails sur OTUD5

Antigène: OTUD5 (OTU Domain Containing 5 (OTUD5))

Autre désignation: OTUD5 (OTUD5 Produits)

Synonymes: anticorps DUBA, anticorps AA407879, anticorps AI553596, anticorps BB114028, anticorps DXImx46e, anticorps Sfc7, anticorps otud5, anticorps si:bz30i22.1, anticorps si:rp71-30i22.1, anticorps zgc:154072, anticorps wu:fi28a06, anticorps zgc:100839, anticorps OTU deubiquitinase 5, anticorps OTU domain containing 5, anticorps OTU deubiquitinase 5a, anticorps OTU deubiquitinase 5 S homeolog, anticorps OTU deubiquitinase 5 L homeolog, anticorps OTU deubiquitinase 5b, anticorps OTUD5, anticorps Otud5, anticorps otud5a, anticorps otud5.S, anticorps otud5.L, anticorps otud5b

Sujet: OTUD5 (ovarian tumor domain-containing 5), also called DUBA (Deubiquitinating enzyme A), is a product of the OTUD5 gene, and a suppressor of the innate immune response via its deubiquitinating activity. The Innate immune systems provide immediate but short-lived defense against infection identified by PRRs, or pattern recognition receptors. OTUD5 cleaves the lysine-63-linked polyubiquitin chains of TRAF3, causing it to dissociate from TBK1, thereby failing to stimulate IFN type 1 production and leading to a suppressed innate immune response.

ID gène: 55593