EGFR anticorps

N° du produit ABIN3026443

Cet anticorps anti-EGFR Monoclonal Souris (Clone B1D8) (ABIN3026443) détecte spécifiquement EGFR dans FACS, IP, AP, Inh et BP. L’anticorps est réactif avec des échantillons de Humain.

Aperçu rapide pour EGFR anticorps (ABIN3026443)

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp EGFR est non-conjugé

Application: Flow Cytometry (FACS), Immunoprecipitation (IP), Affinity Purification (AP), Inhibition (Inh), Blocking Peptide (BP)

Classe de qualité: Carrier-free

Clone: B1D8

Détail du produit anti-EGFR anticorps

Fonction: EGF Receptor Antibody (azide and preservative free)

Aucune reactivité croisée: Souris, Rat (Rattus)

Attributs du produit: This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor. < a href=../search_result.php?search_txt=egfr>EGFR is type I receptor tyrosine kinase with sequence homology to < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.

Purification: Protein G purified monoclonal antibody

Immunogène: Microsomes from A431 cells were used as the immunogen for this antibody.

Isotype: IgG2a, kappa

Information d'application

Indications d'application: The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the antibody to be titered up or down for optimal performance.

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1 mg/mL

Buffer: 1 mg/mL in 1X PBS, BSA free, sodium azide free

Agent conservateur: Azide free

Stock: 4 °C,-20 °C

Stockage commentaire: Store the EGF Receptor antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).

Détails sur EGFR

Antigène: EGFR (Epidermal Growth Factor Receptor (EGFR))

Autre désignation: EGF Receptor

Sujet: This antibody reacts with the extracellular domain of EGF receptor and blocks the EGF/TGFa-induced activation. It also blocks tumor growth in vivo. It is excellent for purification of EGF receptor.< a href=../search_result.php?search_txt=egfr>EGFR is type I receptor tyrosine kinase with sequence homology to < a href=../search_result.php?search_txt=erbb2>ErbB2, -3 -4 or < a href=../search_result.php?search_txt=her2>HER2, -3 -4. It binds to Epidermal Growth Factor (EGF), < a href=../search_result.php?search_txt=TGFa>Transforming Growth Factor-a (TGFa), Heparin-binding EGF (HB-EGF), amphiregulin, betacellulin and epiregulin.

Pathways: Signalisation NF-kappaB, Signalisation RTK, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Stem Cell Maintenance, Hepatitis C, Positive Regulation of Response to DNA Damage Stimulus, Interaction of EGFR with phospholipase C-gamma, Thromboxane A2 Receptor Signaling, EGFR Downregulation, S100 Proteins