BRAF anticorps (AA 344-362)
Aperçu rapide pour BRAF anticorps (AA 344-362) (ABIN3029541)
Antigène
Voir toutes BRAF AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Épitope
- AA 344-362
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Purification
- Antigen affinity
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Immunogène
- Amino acids 344-362 (QPFRPADEDHRNQFGQRDR) were used as the immunogen for this B Raf antibody (100% homologous in human, mouse and rat).
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Isotype
- IgG
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Indications d'application
- The stated application concentrations are suggested starting points. Titration of the B Raf antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL
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Restrictions
- For Research Use only
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Buffer
- 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water
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Stock
- -20 °C
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Stockage commentaire
- After reconstitution, the B Raf antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.
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- BRAF (B-Raf proto-oncogene, serine/threonine kinase (BRAF))
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Autre désignation
- B Raf (BRAF)
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Sujet
- BRAF (v-raf murine sarcoma viral oncogene homolog B1) is a human gene that makes a serine/threonine-protein kinase called B Raf, also known as RAFB1. Northern blot analysis detected transcripts of 10 and 13 kb in cerebrum, fetal brain, and placenta and transcripts of 2.6 and 4.5 kb in testis. Testis also showed lower expression of the 10- and 13-kb transcripts. B Raf is a member of the Raf kinase family of serine/threonine-specific protein kinases. This protein plays a role in regulating the MAP kinase/ERKs signaling pathway, which affects cell division, differentiation, and secretion.
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UniProt
- P15056
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Pathways
- Signalisation MAPK, Signalisation RTK, Neurotrophin Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Hepatitis C, Autophagy
Antigène
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