TFF1 anticorps (Middle Region)

N° du produit ABIN3029764

Détail du produit anti-TFF1 anticorps

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Épitope: Middle Region

Reactivité: Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TFF1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of mouse Estrogen Inducible Protein pS2 (CCFDDSVRGFPWCF) was used as the immunogen for this TFF1 antibody (100% rat homology).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the TFF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the TFF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur TFF1

Antigène: TFF1 (Trefoil Factor 1 (TFF1))

Autre désignation: TFF1 Antibody (Estrogen Inducible Protein) (TFF1 Produits)

Synonymes: anticorps BCEI, anticorps D21S21, anticorps HP1.A, anticorps HPS2, anticorps pNR-2, anticorps pS2, anticorps Bcei, anticorps PS2, anticorps bcei, anticorps d21s21, anticorps hp1.a, anticorps hps2, anticorps p1, anticorps p1-a, anticorps pnr-2, anticorps ps2, anticorps tff1, anticorps xP1, anticorps xp1-L, anticorps xp1, anticorps TFF1, anticorps Ps2, anticorps trefoil factor 1, anticorps trefoil factor 1 S homeolog, anticorps trefoil factor 1, gene 2 S homeolog, anticorps TFF1, anticorps Tff1, anticorps tff1.S, anticorps tff1.2.S, anticorps LOC100358238

Classe de substances: Antibody

Sujet: Trefoil factor 1, also known as Estrogen inducible factor pS2, is a protein that in humans is encoded by the TFF1 gene. Members of the trefoil family are characterized by having at least one copy of the trefoil motif, a 40-amino acid domain that contains three conserved disulfides. They are stable secretory proteins expressed in gastrointestinal mucosa. Their functions are not defined, but they may protect the mucosa from insults, stabilize the mucus layer, and affect healing of the epithelium. It is found that the protein in normal human urine inhibited the growth of calcium oxalate crystals. Urinary TFF1 showed an inhibitory potency similar to that of nephrocalcin, and inhibition was dose dependent and inhibited by TFF1 antisera, particularly by antisera directed to the TFF1 C terminus. Concentrations and relative amounts of the protein in the urine of patients with idiopathic calcium oxalate kidney stones were significantly less than those found in controls. This gene, which is expressed in the gastric mucosa, has also been studied because of its expression in human tumors. This gene and two other related trefoil family member genes are found in a cluster on chromosome 21.

UniProt: Q08423

Pathways: EGFR Signaling Pathway