ALOX5 anticorps (AA 120-483)

N° du produit ABIN3030014

Détail du produit anti-ALOX5 anticorps

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Épitope: AA 120-483

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ALOX5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 120-483) was used as the immunogen for this 5-Lipoxygenase antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the 5-Lipoxygenase antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the 5-Lipoxygenase antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur ALOX5

Antigène: ALOX5 (Arachidonate 5-Lipoxygenase (ALOX5))

Autre désignation: 5-Lipoxygenase (ALOX5 Produits)

Synonymes: anticorps 5-LO, anticorps 5-LOX, anticorps 5LPG, anticorps LOG5, anticorps 5LO, anticorps 5LX, anticorps AI850497, anticorps F730011J02, anticorps LOX5A, anticorps si:dkey-194n13.2, anticorps lox5, anticorps arachidonate 5-lipoxygenase, anticorps arachidonate 5-lipoxygenase a, anticorps Arachidonate 5-lipoxygenase, anticorps ALOX5, anticorps Alox5, anticorps alox5a, anticorps AFUA_4G02770, anticorps AOR_1_1362014, anticorps lox5

Sujet: Arachidonate 5-lipoxygenase, also known as 5-LOX or 5-LO, is an enzyme that in humans is encoded by the ALOX5 gene. It is a member of the lipoxygenase family of enzymes. It is mapped to 10q11.21. ALOX5 plays a dual role in the synthesis of leukotrienes from arachidonic acid. Its position within the nucleus of resting cells determines the capacity to generate LTB4 upon subsequent activation. It is involved in lung vascular tone regulation and in the development of chronic pulmonary hypertension in hypoxic rodent models. ALOX5 also transforms EFAs into leukotrienes and is a current target for pharmaceutical intervention in a number of diseases.

ID gène: 240