CCR6 anticorps (C-Term)

N° du produit ABIN3030496

Détail du produit anti-CCR6 anticorps

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp CCR6 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human CCR6 (RQTSETADNDNASSFTM) was used as the immunogen for this CCR6 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the CCR6 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the CCR6 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur CCR6

Antigène: CCR6 (Chemokine (C-C Motif) Receptor 6 (CCR6))

Autre désignation: CCR6 (CCR6 Produits)

Synonymes: anticorps BN-1, anticorps C-C CKR-6, anticorps CC-CKR-6, anticorps CCR-6, anticorps CD196, anticorps CKR-L3, anticorps CKRL3, anticorps CMKBR6, anticorps DCR2, anticorps DRY6, anticorps GPR29, anticorps GPRCY4, anticorps STRL22, anticorps Cmkbr6, anticorps KY411, anticorps C-C motif chemokine receptor 6, anticorps chemokine (C-C motif) receptor 6, anticorps CCR6, anticorps Ccr6

Sujet: CCR6, also termed CKRL3, encodes a 369-amino acid polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4-kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.

UniProt: P51684

Pathways: cAMP Metabolic Process