Factor VIII anticorps (Middle Region)

N° du produit ABIN3030544

Détail du produit anti-Factor VIII anticorps

Antigène: Factor VIII (F8) (Coagulation Factor VIII (F8))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Factor VIII est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of human F8 (APVLQDFRSLNDSTN) was used as the immunogen for this Factor VIII antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Factor VIII antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Factor VIII antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Factor VIII

Antigène: Factor VIII (F8) (Coagulation Factor VIII (F8))

Autre désignation: Factor VIII (F8 Produits)

Synonymes: anticorps fb61d02, anticorps wu:fb61d02, anticorps Cf-8, anticorps Cf8, anticorps FVIII, anticorps AHF, anticorps DXS1253E, anticorps F8B, anticorps F8C, anticorps HEMA, anticorps coagulation factor VIIi, anticorps coagulation factor VIII, anticorps coagulation factor VIII, procoagulant component, anticorps f7i, anticorps F8

Sujet: Coagulation Factor VIII (FVIII) is an essential blood-clotting protein. By in situ hybridization, Tantravahi et al.(1986) concluded that the F8 gene is located in the proximal part of chromosome Xq28 with probes DX13 and St14 distally located. The F8 gene encodes coagulation Factor VIII, a large plasma glycoprotein that functions in the blood coagulation cascade as a cofactor for the F9a-dependent activation of F10. Factor VIII is activated proteolytically by a variety of coagulation enzymes, including thrombin(F2). It is tightly associated in the blood with VWF, which serves as a protective carrier protein for Factor VIII (Toole et al., 1984, Hoyer, 1994).

UniProt: P00451