COL3A1 anticorps (C-Term)

N° du produit ABIN3030551

Détail du produit anti-COL3A1 anticorps

Antigène: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp COL3A1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: C-terminal amino acids VGAAAIAGIGGEKAGGFAPYYG were used as the immunogen for this Collagen III antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Collagen III antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Collagen III antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur COL3A1

Antigène: COL3A1 (Collagen, Type III, alpha 1 (COL3A1))

Autre désignation: Collagen III / COL3A1 (COL3A1 Produits)

Synonymes: anticorps EDS4A, anticorps AW550625, anticorps Col3a-1, anticorps MMS10-W, anticorps Ms10w, anticorps mKIAA4231, anticorps col3a1, anticorps collagen type III alpha 1 chain, anticorps collagen, type III, alpha 1, anticorps collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog, anticorps COL3A1, anticorps Col3a1, anticorps col3a1, anticorps col3a1.S

Sujet: COL3A1, also called EDS4A or Collagen alpha-1(III), is a protein that in humans is encoded by the COL3A1 gene, it is mapped to 2q32.2. COL3A1 chain is a fibrillar-forming collagen comprising 3 alpha-1(III) chains and is expressed in early embryos and throughout embryogenesis. In adult, COL3A1 is a major component of the extracellular matrix in a variety of internal organs and skin. COL3A1 is also a fibrous scleroprotein in bone, cartilage, dentin, tendon, bone marrow stroma and other connective tissue. It is involved in regulation of cortical development, and it Is the major ligand of GPR56 in the developing brain.COL3A1 binding to GPR56 can inhibit neuronal migration and activate the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12

ID gène: 1281

Pathways: Autophagy, Growth Factor Binding