EIF2S1 anticorps (Middle Region)

N° du produit ABIN3030881

Détail du produit anti-EIF2S1 anticorps

Antigène: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Épitope: Middle Region

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp EIF2S1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the middle region of human Eukaryotic Translation Initiation Factor 2 subunit 1 (KDEQLESLFQRTAWV) was used as the immunogen for this EIF2A antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the EIF2S1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the EIF2S1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur EIF2S1

Antigène: EIF2S1 (Eukaryotic Translation Initiation Factor 2 Subunit 1 (EIF2S1))

Autre désignation: EIF2S1 (EIF2S1 Produits)

Synonymes: anticorps EIF-2, anticorps EIF-2A, anticorps EIF-2alpha, anticorps EIF2, anticorps EIF2A, anticorps Eif2s1, anticorps eif2s1l, anticorps fb36a08, anticorps wu:fb36a08, anticorps zgc:56510, anticorps 0910001O23Rik, anticorps 2410026C18Rik, anticorps 35kDa, anticorps Eif2a, anticorps eIF2alpha, anticorps eif2a, anticorps CG9946, anticorps Dmel\\CG9946, anticorps Eif2alpha, anticorps IF2A_DROME, anticorps M(1)14C, anticorps M(1)19-153, anticorps M(1)8e3-10, anticorps deIF2alpha, anticorps eIF-2, anticorps eIF-2 a, anticorps eIF-2 alpha, anticorps eIF2 alpha, anticorps eIF2-alpha, anticorps eIF2a, anticorps eiF-2alpha, anticorps elF2alpha, anticorps l(1)14Cf, anticorps l(1)19-153, anticorps eukaryotic translation initiation factor 2 subunit alpha, anticorps eukaryotic translation initiation factor 2, subunit 1 alpha a, anticorps eukaryotic translation initiation factor 2, subunit 1 alpha, anticorps eukaryotic translation initiation factor 2 alpha subunit, anticorps Eukaryotic translation initiation factor 2 subunit 1, anticorps eukaryotic translation initiation factor 2 subunit alpha L homeolog, anticorps eukaryotic translation Initiation Factor 2alpha, anticorps EIF2S1, anticorps eif2s1a, anticorps Eif2s1, anticorps eif2s1, anticorps LOC693063, anticorps CNI00230, anticorps THAPSDRAFT_105, anticorps if2a, anticorps eif2s1.L, anticorps eIF-2alpha

Sujet: Eukaryotic Translation Initiation Factor 2, Subunit 1, also called EIF2-alpha or EIF2A, is a protein that in humans is encoded by the EIF2S1 gene. Hartz(2010) mapped the gene to chromosome 14q23.3 based on an alignment of the EIF2S1 sequence with the genomic sequence (GRCh37). Ernst et al.(1987) stated that protein synthesis is inhibited due to phosphorylation of EIF2S1 in hemin-deprived rabbit reticulocyte lysates. HeLa cells subjected to heat shock, serum deprivation, or interferon treatment followed by virus infection also show a correlation between EIF2S1 phosphorylation and translational repression. Jacob et al.(1989) found that the alpha-Pal transcription factor bound to two palindromic sites within the EIF2S1 promoter and was essential for transcription of the gene.

UniProt: P05198

Pathways: Ribonucleoprotein Complex Subunit Organization, ER-Nucleus Signaling, Hepatitis C