FAF1 anticorps (N-Term)

N° du produit ABIN3030906

Détail du produit anti-FAF1 anticorps

Antigène: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAF1 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the N-terminus of human FAF1 (MASNMDREMILADFQACTGIEN) was used as the immunogen for this FAF1 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the FAF1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the FAF1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur FAF1

Antigène: FAF1 (Fas (TNFRSF6) Associated Factor 1 (FAF1))

Autre désignation: FAF1 (FAF1 Produits)

Synonymes: anticorps faf1, anticorps MGC53741, anticorps MGC80303, anticorps FAF1, anticorps zgc:55752, anticorps wu:fc25h12, anticorps HFAF1s, anticorps UBXD12, anticorps UBXN3A, anticorps hFAF1, anticorps AA408698, anticorps Dffrx, anticorps Fam, anticorps Fas (TNFRSF6) associated factor 1 S homeolog, anticorps Fas (TNFRSF6) associated factor 1 L homeolog, anticorps Fas associated factor 1, anticorps Fas (TNFRSF6) associated factor 1, anticorps Fas-associated factor 1, anticorps faf1.S, anticorps faf1.L, anticorps FAF1, anticorps faf1, anticorps Faf1

Sujet: Fas-associated factor-1(FAF1) is a Fas-binding pro-apoptotic protein that is a component of the death-inducing signaling complex in Fas-mediated apoptosis. FAF1 is involved in negative regulation of NF-kappaB activation. In addition to the previously known function as a component of the Fas death-inducing signaling complex, i.e. NF-kappaB activity suppressor by cytoplasmic retention of NF-kappaB p65 via physical interaction. hFAF1 was expressed abundantly in testis, skeletal muscle, and heart as 2.8 kb mRNA. Polyclonal antibody against hFAF1 detected 74 kD protein, a deduced protein size from the ORF and 40 kD protein in some cell lines.

UniProt: Q9UNN5

Pathways: Maintenance of Protein Location