HAVCR1 anticorps (C-Term)

N° du produit ABIN3031181

Détail du produit anti-HAVCR1 anticorps

Antigène: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Épitope: C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp HAVCR1 est non-conjugé

Application: Western Blotting (WB), Immunocytochemistry (ICC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human KIM-1 (IKALQNAVEKEVQAEDN) was used as the immunogen for this KIM-1 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the KIM-1 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL,Immunocytochemistry: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the KIM-1 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur HAVCR1

Antigène: HAVCR1 (Hepatitis A Virus Cellular Receptor 1 (HAVCR1))

Autre désignation: KIM-1 (HAVCR1 Produits)

Synonymes: anticorps HAVCR, anticorps HAVCR-1, anticorps KIM-1, anticorps KIM1, anticorps TIM, anticorps TIM-1, anticorps TIM1, anticorps TIMD-1, anticorps TIMD1, anticorps Kim1, anticorps HAVCR1, anticorps LOC100226241, anticorps AI503787, anticorps Tim1, anticorps Timd1, anticorps hepatitis A virus cellular receptor 1, anticorps hepatitis A virus cellular receptor 1 homolog, anticorps HAVCR1, anticorps Havcr1, anticorps LOC100226241

Classe de substances: Virus

Sujet: Kidney injury molecule 1, also known as HAVCR1, HAVCR or TIM1, is a protein that in humans is encoded by the KIM1 gene. The KIM-1 protein is a receptor for virus through the infection of canine osteogenic sarcoma cells expressing HAVCR1 with HAV. Using a monoclonal antibody to mouse KIM-1, it was found the protein expressed after activation of naive T cells and on T cells differentiated in Th2-polarizing conditions. Ectopic expression of KIM-1 during mouse T-cell differentiation leads to production of the Th2-type cytokine IL4, but not the Th1-type cytokine Ifng. KIM1-expressing epithelial cells internalized apoptotic bodies, and the protein is directly responsible for phagocytosis in cultured primary rat tubule epithelial cells and in porcine and canine epithelial cell lines.

UniProt: Q96D42