IRF8 anticorps (C-Term)

N° du produit ABIN3031423

Détail du produit anti-IRF8 anticorps

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp IRF8 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human Interferon regulatory factor 8 (ASHQRSFFRENQQITV) was used as the immunogen for this IRF8 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the IRF8 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the IRF8 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur IRF8

Antigène: IRF8 (Interferon Regulatory Factor 8 (IRF8))

Autre désignation: IRF8 (IRF8 Produits)

Synonymes: anticorps zgc:92252, anticorps IRF8, anticorps MGC140338, anticorps DKFZp469B0320, anticorps H-ICSBP, anticorps ICSBP, anticorps ICSBP1, anticorps IRF-8, anticorps icsbp1, anticorps AI893568, anticorps Icsbp1, anticorps Myls, anticorps interferon regulatory factor 8, anticorps interferon regulatory factor 8 L homeolog, anticorps irf8, anticorps IRF8, anticorps irf8.L, anticorps Irf8

Sujet: Interferon regulatory factor 8, also known as Interferon consensus sequence-binding protein (ICSBP), is a protein that in humans is encoded by the IRF8 gene. By genomic sequence analysis, the gene is mapped to chromosome 16q24.1. It is a transcription factor of the interferon regulatory factor (IRF) family. The IRF family proteins bind to the IFN-stimulated response element (ISRE) and regulate expression of genes stimulated by type I IFNs, namely IFNalpha and IFNbeta. IRF family proteins also control expression of IFNalpha and IFNbeta-regulated genes that are induced by viral infection. IRF8 is a transcription factor that plays critical roles in the regulation of lineage commitment and in myeloid cell maturation including the decision for a common myeloid progenitor(CMP) to differentiate into a monocyte precursor cell.

UniProt: Q02556

Pathways: Cellular Response to Molecule of Bacterial Origin