PER2 anticorps (AA 13-330)

N° du produit ABIN3032182

Détail du produit anti-PER2 anticorps

Antigène: PER2 (Period Circadian Protein 2 (PER2))

Épitope: AA 13-330

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PER2 est non-conjugé

Application: Western Blotting (WB)

Purification: Antigen affinity

Immunogène: Human partial recombinant protein (AA 13-330) was used as the immunogen for this PER2 antibody.

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the PER2 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the PER2 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur PER2

Antigène: PER2 (Period Circadian Protein 2 (PER2))

Autre désignation: PER2 (PER2 Produits)

Synonymes: anticorps FASPS, anticorps FASPS1, anticorps mKIAA0347, anticorps mPer2, anticorps rPER2, anticorps gPer2, anticorps fj43b09, anticorps wu:fj43b09, anticorps period circadian regulator 2, anticorps period circadian clock 2, anticorps PER2, anticorps Per2, anticorps per2

Sujet: Period circadian protein homolog 2 is a member of the Period family of proteins and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. It has been showed that PER2 can positively stimulate activity of the Bmal1-Npas2 transcription complex and, in turn, Npas2 transcriptionally regulates delta-aminolevulinate synthase. It is involved in a negative-feedback loop that attenuates estrogen stimulation and links the circadian cycle to estrogen receptor signaling. The rhythmic levels of PER2 are critical for circadian oscillations in cells and intact organisms. The protein also functions in tumor suppression by regulating DNA damage-responsive pathways.

ID gène: 8864