Peroxiredoxin 5 anticorps (C-Term)

N° du produit ABIN3032191

Détail du produit anti-Peroxiredoxin 5 anticorps

Antigène: Peroxiredoxin 5 (PRDX5)

Épitope: C-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Peroxiredoxin 5 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purification: Antigen affinity

Immunogène: An amino acid sequence from the C-terminus of human PRDX5 (DDSLVSIFGNRRLKRF) was used as the immunogen for this Peroxiredoxin 5 antibody (100% homologous in human, mouse and rat).

Isotype: IgG

Information d'application

Indications d'application: The stated application concentrations are suggested starting amounts. Titration of the Peroxiredoxin 5 antibody may be required due to differences in protocols and secondary/substrate sensitivity.\. Western blot: 0.5-1 μg/mL,IHC (Paraffin): 0.5-1 μg/mL

Restrictions: For Research Use only

Stockage

Buffer: 0.5 mg/mL if reconstituted with 0.2 mL sterile DI water

Stock: -20 °C

Stockage commentaire: After reconstitution, the Peroxiredoxin 5 antibody can be stored for up to one month at 4°C. For long-term, aliquot and store at -20°C. Avoid repeated freezing and thawing.

Détails sur Peroxiredoxin 5

Antigène: Peroxiredoxin 5 (PRDX5)

Abstract: PRDX5 Produits

Synonymes: anticorps acr1, anticorps aoeb166, anticorps pmp20, anticorps prx-5, anticorps prx5, anticorps prxv, anticorps sbbi10, anticorps GB16965, anticorps zgc:112318, anticorps PRDX5, anticorps CG 32920, anticorps CG 7217, anticorps CG32920, anticorps CG7217, anticorps Dmel\\CG7217, anticorps dPrx5, anticorps dprx5, anticorps ACR1, anticorps AOEB166, anticorps B166, anticorps PLP, anticorps PMP20, anticorps PRDX6, anticorps PRXV, anticorps prx-V, anticorps AOPP, anticorps Pmp20, anticorps Prdx6, anticorps PrxV, anticorps Aoeb166, anticorps Prx V, anticorps peroxiredoxin 5 L homeolog, anticorps peroxiredoxin-5, mitochondrial, anticorps peroxiredoxin 5, anticorps Peroxiredoxin 5, anticorps prdx5.L, anticorps LOC552429, anticorps prdx5, anticorps PRDX5, anticorps Prx5, anticorps Prdx5

Sujet: Peroxiredoxin 5, also known as PRX5 and PRDX5, is a member of the peroxiredoxin family and may play an antioxidant protective role in various tissues under nonpathologic conditions and during inflammatory processes. PRDX5 displays mitochondrial presequence features and has 3 cysteines implicated in antioxidant activity and a C-terminal SQL peroxisomal targeting sequence. Northern blot analysis revealed ubiquitous expression of a 1.0-kb PRDX5 transcript in tissues and cell lines. Functional analysis showed that Peroxiredoxin 5 has antioxidant activity equivalent to that of CAT. While PRDX5 was localized to fibroblasts in normal tendon, it was localized to fibroblasts and endothelial cells in degenerative tendon. mRNA and protein levels increased at 12 hours, and the increase in PRDX5 expression correlated with reduced peroxide levels. Peroxiredoxin 5 plays a protective role against oxidative stress in human cartilage.

UniProt: P30044

Pathways: Cell RedoxHomeostasis