FAIM2 anticorps (N-Term)

N° du produit ABIN303262

Détail du produit anti-FAIM2 anticorps

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Épitope: N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp FAIM2 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: Recognizes 16 amino acid peptide from near the amino terminus of Human LFG.

Réactivité croisée (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: Immunoaffinity Chromatography.

Immunogène: Synthetic Peptide corresponding to 16 amino acid peptide from near the amino terminus of human LFG.

Information d'application

Indications d'application: Immunohistochemistry on Paraffin Sections (5 μg/mL). Western Blot.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS containing 0.02 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at-20 °C for longer. Dilute only prior to immediate use.

Détails sur FAIM2

Antigène: FAIM2 (Fas Apoptotic Inhibitory Molecule 2 (FAIM2))

Autre désignation: FAIM2 (FAIM2 Produits)

Synonymes: anticorps FAIM2, anticorps faim2, anticorps MGC84041, anticorps zgc:110143, anticorps MGC146456, anticorps LFG, anticorps LFG2, anticorps NGP35, anticorps NMP35, anticorps TMBIM2, anticorps 2900002L20Rik, anticorps Lfg, anticorps Lfg2, anticorps NMP25, anticorps Nmp35, anticorps Fas apoptotic inhibitory molecule 2, anticorps Fas apoptotic inhibitory molecule 2 L homeolog, anticorps Fas apoptotic inhibitory molecule 2a, anticorps fas apoptotic inhibitory molecule 2, anticorps FAIM2, anticorps faim2, anticorps faim2.L, anticorps faim2a, anticorps CpipJ_CPIJ015441, anticorps Faim2

Sujet: Programmed cell death regulates a number of biological processes such as normal organism development, tissue homeostasis, and removal of damaged cells. Disruption of this process has been implicated in a variety of diseases such as cancer. FAIM2 is a recently identified protein that can inhibit the apoptotic signal transduced by the Fas receptor but not from the related tumor necrosis factor-alpha death signal. In this respect, FAIM2 is functionally similar to the anti-apoptotic proteins FAIM, FLIP and Bcl-xL. FAIM2, a seven membrane spanning protein, can bind the Fas receptor but does not regulate Fas expression or inhibit binding of FADD to Fas. FAIM2 is widely distributed, but highly expressed in the hippocampus and other neural tissues. FAIM2 was also identified as the neural membrane protein 35 (NMP35) and its expression is known to be regulated by the Phosphatidylinositol 3-kinase-Akt/PKB pathway.Synonyms: Fas apoptotic inhibitory molecule 2, KIAA0950, LFG, Protein lifeguard, TMBIM2, Transmembrane BAX inhibitor motif-containing protein 2

ID gène: 23017

NCBI Accession: NP_036438

UniProt: Q9BWQ8