MFN1 anticorps (N-Term)

N° du produit ABIN3042361

Détail du produit anti-MFN1 anticorps

Antigène: MFN1 (Mitofusin 1 (MFN1))

Épitope: AA 23-49, N-Term

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MFN1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Mitofusin-1(MFN1) detection. Tested with WB in Human,Mouse,Rat.

Séquence: DQLLEFVTEG SHFVEATYKN PELDRIA

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Mitofusin-1(MFN1) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: mitofusin 1
Protein Name: Mitofusin-1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the N-terminal of human Mitofusin 1 (23-49aa DQLLEFVTEGSHFVEATYKNPELDRIA), different from the related mouse and rat sequences by one amino acid.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for Mitofusin 1 is approximately 0.25 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur MFN1

Antigène: MFN1 (Mitofusin 1 (MFN1))

Autre désignation: MFN1 (MFN1 Produits)

Synonymes: anticorps mfn1, anticorps zgc:66150, anticorps mitofusin-1, anticorps MFN1, anticorps MFN2, anticorps hfzo1, anticorps hfzo2, anticorps 2310002F04Rik, anticorps 6330416C07Rik, anticorps D3Ertd265e, anticorps HR2, anticorps mKIAA4032, anticorps Fzo1b, anticorps mitofusin 1b, anticorps mitofusin 1, anticorps mitofusin 1 S homeolog, anticorps mfn1b, anticorps MFN1, anticorps mfn1.S, anticorps mfn1, anticorps Mfn1

Sujet: Mitofusin-1 is a protein that in humans is encoded by the MFN1 gene. It is an 80-90 kDa mitochondrial member of the dynamin family of molecules. It is ubiquitously expressed, and found in the outer mitochondrial membrane. The protein encoded by this gene is a mediator of mitochondrial fusion, and thereby contribute to the dynamic balance between fusion and fission that determines mitochondria morphology. MFN1 is known to form oligomers, either with itself or MFN-2, and to undergo ubiquitination by MARCH5. MFN-1 has two key domains. One is a coiled-coil region that mediates MFN-1: MFN-1/2 binding, and a second is a GTPase domain whose cleavage of GTP is necessary for membrane fusion. Overexpression of MFN1 caused perinuclear mitochondrial clustering.

Synonyms: Fzo homolog antibody|Hfzo1 antibody|Hfzo2 antibody|MFN 1 antibody|Mfn1 antibody|MFN1_HUMAN antibody|Mitochondrial transmembrane GTPase Fzo 1 antibody|Mitochondrial transmembrane GTPase FZO 2 antibody|Mitochondrial transmembrane GTPaseFZO1B antibody|Mitofusin 1 antibody|Mitofusin-1 antibody|Mitofusin1 antibody|Putative transmembrane GTPase antibody|Transmembrane GTPase MFN1 antibody

ID gène: 55669