GBP1 anticorps (C-Term)

N° du produit ABIN3042677

Détail du produit anti-GBP1 anticorps

Antigène: GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

Épitope: AA 566-589, C-Term

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GBP1 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Guanylate-binding protein 1(GBP1) detection. Tested with WB in Human.

Séquence: QKESRIMKNE IQDLQTKMRR RKAC

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Guanylate-binding protein 1(GBP1) detection. Tested with WB in Human.
Gene Name: guanylate binding protein 1, interferon-inducible
Protein Name: Guanylate-binding protein 1

Purification: Immunogen affinity purified.

Immunogène: A synthetic peptide corresponding to a sequence at the C-terminus of human GBP1(566-589aa QKESRIMKNEIQDLQTKMRRRKAC).

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.

Agent conservateur: Thimerosal (Merthiolate), Sodium azide

Précaution d'utilisation: This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Date de péremption: 12 months

Détails sur GBP1

Antigène: GBP1 (Guanylate Binding Protein 1, Interferon-Inducible (GBP1))

Autre désignation: GBP1 (GBP1 Produits)

Synonymes: anticorps guanylate binding protein 1, anticorps guanylate binding protein 1, interferon-inducible, anticorps guanylate binding protein 1, interferon-inducible, 67kD, anticorps GBP1, anticorps Gbp1, anticorps gbp1

Sujet: Interferons induce a large number of genes in their target cells, including those coding for guanylate-binding proteins(GBPs). GBPs, such as GBP1, are characterized by their ability to specifically bind guanine nucleotides(GMP, GDP, and GTP) and are distinguished from the GTP-binding proteins by the presence of 2 binding motifs rather than 3. The 593-amino acid GBP1 protein shares 77 % and 88 % identity with GBP2 and GBP3, respectively. All GBPs, including GBP1, have a conserved N-terminal globular GTP-binding domain containing 2 consensus sequences and a third T(L/V)RD sequence not found in other GTPases. The GBP1 gene to the GBP gene cluster on chromosome 1p22.2. It is located telomeric to GBP2 and centromeric to GBP3. High expression of GBP1, GBP2, and GBP3 are in endothelial cells after stimulation with IFNG, TNF, or IL1B .

Synonyms: GBP 1 antibody|GBP-1 antibody|GBP1 antibody|GBP1_HUMAN antibody|GTP binding protein 1 antibody|GTP-binding protein 1 antibody|Guanine nucleotide binding protein 1 antibody|Guanine nucleotide-binding protein 1 antibody|Guanylate binding protein 1 antibody|Guanylate binding protein 1 interferon inducible 67 kDa antibody|Guanylate binding protein 1 interferon inducible antibody|HuGBP 1 antibody|HuGBP-1 antibody|HuGBP1 antibody|Interferon induced guanylate binding protein 1 antibody|Interferon-induced guanylate-binding protein 1 antibody|OTTHUMP00000012352 antibody

UniProt: P32455

Pathways: Cellular Response to Molecule of Bacterial Origin