SDHA anticorps (AA 44-380)

N° du produit ABIN3043324

Détail du produit anti-SDHA anticorps

Antigène: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Épitope: AA 44-380

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SDHA est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial(SDHA) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)
Protein Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human SDHA recombinant protein (Position: S44-L380). Human SDHA shares 98.2% and 97.6% amino acid (aa) sequence identity with mouse and rat SDHA, respectively.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur SDHA

Antigène: SDHA (Succinate Dehydrogenase Complex, Subunit A, Flavoprotein (Fp) (SDHA))

Autre désignation: SDHA (SDHA Produits)

Synonymes: anticorps CG17246, anticorps Dmel\\CG17246, anticorps Scs-fp, anticorps Sdh, anticorps Sdha, anticorps scs-fp, anticorps sdh, anticorps CMD1GG, anticorps FP, anticorps PGL5, anticorps SDH1, anticorps SDH2, anticorps SDHF, anticorps 1500032O14Rik, anticorps 2310034D06Rik, anticorps 4921513A11, anticorps C81073, anticorps im:7141001, anticorps zgc:56051, anticorps Fp, anticorps sdha-b, anticorps Succinate dehydrogenase, subunit A (flavoprotein), anticorps succinate dehydrogenase complex flavoprotein subunit A, anticorps succinate dehydrogenase complex, subunit A, flavoprotein (Fp), anticorps succinate dehydrogenase complex subunit A, flavoprotein (Fp) S homeolog, anticorps SdhA, anticorps SDHA, anticorps Sdha, anticorps sdha, anticorps sdha.S

Sujet: Complex II of the mitochondrial respiratory chain, also known as succinate dehydrogenase or succinate:ubiquinone oxidoreductase, consists of 4 nuclear-encoded polypeptides, these are the flavoprotein subunit (SDHA), the iron sulfur protein subunit (SDHB), and the integral membrane protein subunits SDHC and SDHD. SDHA is an acronym for succinate dehydrogenase complex subunit A. The succinate dehydrogenase (SDH) protein complex catalyzes the oxidation of succinate (succinate + ubiquinone => fumarate + ubiquinol). The SDHA subunit is connected to the SDHB subunit on the hydrophilic, catalytic end of the complex, and weighs 72.7 kDA. Mutations in the SDHA subunit have a distinct pathology from mutations in the SDHB/SDHC/SDHD subunits, it is the only subunit to never have shown tumor suppressor behaviour. Heterozygous carriers of an SDHA mutation do not develop paragangliomas as has been seen for mutations in the other subunits. This appears to be due to the expression of two similar SDHA genes (Types I and II) in the paraganglia system.

Synonyms: MD1GG antibody|DHSA_HUMAN antibody|Flavoprotein subunit of complex II antibody|FP antibody| PGL5 antibody|SDH 2 antibody|SDH1 antibody|SDH2 antibody|SDHA antibody|SDHF antibody| Succinate dehydrogenase [ubiquinone] flavoprotein subunit antibody|Succinate dehydrogenase [ubiquinone] flavoprotein subunit mitochondrial antibody|Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial antibody|Succinate dehydrogenase complex flavoprotein subunit antibody|Succinate dehydrogenase complex flavoprotein subunit precursor antibody|Succinate dehydrogenase complex subunit A antibody| Succinate dehydrogenase complex subunit A flavoprotein antibody

ID gène: 6389

UniProt: P31040