SLC1A2 anticorps (AA 461-574)

N° du produit ABIN3043436

Détail du produit anti-SLC1A2 anticorps

Antigène: SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))

Épitope: AA 461-574

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp SLC1A2 est non-conjugé

Application: Western Blotting (WB)

Fonction: Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 2(SLC1A2) detection. Tested with WB in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Excitatory amino acid transporter 2(SLC1A2) detection. Tested with WB in Human,Mouse,Rat.
Gene Name: solute carrier family 1 (glial high affinity glutamate transporter), member 2
Protein Name: Excitatory amino acid transporter 2

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human EAAT2 recombinant protein (Position: T461-K574). Human EAAT2 shares 96% amino acid (aa) sequence identity with both mouse and rat EAAT2.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human, Mouse, Rat, The detection limit for EAAT2 is approximately 0.1 ng/lane under reducing conditions.
Notes: Tested Species: Species with positive results.
Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB.

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Références pour anticorps anti-SLC1A2 (ABIN3043436)

Ding, Zhang, Liu, Zhang, Ma, Bruce, Zhang: "Tumor necrosis factor-? promotes the expression of excitatory amino-acid transporter 2 in astrocytes: Optimal concentration and incubation time." dans: Experimental and therapeutic medicine, Vol. 8, Issue 6, pp. 1909-1913, (2014) (PubMed).

Détails sur SLC1A2

Antigène: SLC1A2 (Solute Carrier Family 1 (Glial High Affinity Glutamate Transporter), Member 2 (SLC1A2))

Autre désignation: SLC1A2 (SLC1A2 Produits)

Synonymes: anticorps CG3159, anticorps Dmel\\CG3159, anticorps EAAT, anticorps dEAAT2, anticorps dEaat2, anticorps Eaat, anticorps GB16377, anticorps EAAT2, anticorps SLC1A2, anticorps Eaat2, anticorps Glt, anticorps Glt-1, anticorps GLT-1, anticorps 1700091C19Rik, anticorps 2900019G14Rik, anticorps AI159670, anticorps GLT1, anticorps MGLT1, anticorps eaat2, anticorps fj34b12, anticorps slc1a2, anticorps wu:fj34b12, anticorps zgc:65897, anticorps Excitatory amino acid transporter 2, anticorps excitatory amino acid transporter 2, anticorps solute carrier family 1 member 2, anticorps solute carrier family 1 (glial high affinity glutamate transporter), member 2, anticorps solute carrier family 1 (glial high affinity glutamate transporter), member 2b, anticorps Eaat2, anticorps Eaat-2, anticorps SLC1A2, anticorps VDBG_06180, anticorps EUBELI_01747, anticorps Trebr_0139, anticorps Slc1a2, anticorps slc1a2b

Sujet: SLC1A2 is also known as EAAT2 or GLT-1. This gene encodes a member of a family of solute transporter proteins. The membrane-bound protein is the principal transporter that clears the excitatory neurotransmitter glutamate from the extracellular space at synapses in the central nervous system. Glutamate clearance is necessary for proper synaptic activation and to prevent neuronal damage from excessive activation of glutamate receptors. Mutations in and decreased expression of this protein are associated with amyotrophic lateral sclerosis. Alternatively spliced transcript variants of this gene have been identified.

Synonyms: EAA2_HUMAN antibody|EAAT2 antibody|Excitatory amino acid transporter 2 antibody|Excitotoxic amino acid transporter 2 antibody|Glial high affinity glutamate transporter antibody|GLT 1 antibody|GLT1 antibody|Glutamate aspartate transporter II antibody|Glutamate transporter 1 antibody|Glutamate/aspartate transporter II antibody|Slc1a2 antibody|Sodium dependent glutamate aspartate transporter 2 antibody|Sodium-dependent glutamate/aspartate transporter 2 antibody|solute carrier family 1 (glial high affinity glutamate transporter), member 2 antibody|Solute carrier family 1 glial high affinity glutamate transporter member 2 antibody|Solute carrier family 1 member 2 antibody

ID gène: 6506

UniProt: P43004

Pathways: Dicarboxylic Acid Transport