BMPR1B anticorps (AA 14-184)

N° du produit ABIN3043801

Détail du produit anti-BMPR1B anticorps

Antigène: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Épitope: AA 14-184

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp BMPR1B est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Bone morphogenetic protein receptor type-1B(BMPR1B) detection. Tested with WB, IHC-P in Human.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Bone morphogenetic protein receptor type-1B(BMPR1B) detection. Tested with WB, IHC-P in Human.
Gene Name: bone morphogenetic protein receptor, type IB
Protein Name: Bone morphogenetic protein receptor type-1B

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human BMPR1B recombinant protein (Position: K14-Q184). Human BMPR1B shares 97.1% amino acid (aa) sequence identity with mouse BMPR1B.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Human
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur BMPR1B

Antigène: BMPR1B (Bone Morphogenetic Protein Receptor, Type IB (BMPR1B))

Autre désignation: BMPR1B (BMPR1B Produits)

Synonymes: anticorps ALK6, anticorps BMPR-IB, anticorps FecB, anticorps alk-6, anticorps alk6, anticorps cdw293, anticorps alk6b, anticorps zgc:172219, anticorps BMPR1B, anticorps AI385617, anticorps ALK-6, anticorps AV355320, anticorps Acvrlk6, anticorps Alk6, anticorps BMPR-1B, anticorps CFK-43a, anticorps SKR6, anticorps BR1b, anticorps alk6tr, anticorps bmpr1b, anticorps zALK-6, anticorps zgc:92220, anticorps CDw293, anticorps BMP15, anticorps BMPRIB, anticorps RPK-1, anticorps bone morphogenetic protein receptor type 1B, anticorps bone morphogenetic protein receptor, type IBb, anticorps bone morphogenetic protein receptor, type 1B, anticorps bone morphogenetic protein receptor, type IBa, anticorps BMPR1B, anticorps bmpr1b, anticorps bmpr1bb, anticorps Bmpr1b, anticorps bmpr1ba

Sujet: BMPR1B (Bone Morphogenetic Protein Receptor Type IB), also known as ALK6, is a protein which in humans is encoded by the BMPR1B gene. BMPR1B is a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding. By analysis of a monochromosome hybrid mapping panel and by FISH, Astrom et al. (1999) mapped the BMPR1B gene to chromosome 4q22-q24. Ide et al. (1997) compared BMP receptor expression in normal and cancerous prostate tissues. While BMPR1A and BMPR2 were expressed at similar levels in all prostate tissues, BMPR1B was expressed at a significantly reduced level in cancerous prostate tissue.

Synonyms: Activin receptor like kinase 6 antibody|Acvrlk6 antibody|ALK 6 antibody|ALK6 antibody| alk6tr antibody|BMP type-1B receptor antibody|BMPR IB antibody|BMPR-1B antibody|Bmpr1b antibody|BMPRIB antibody|BMR1B_HUMAN antibody|Bone morphogenetic protein receptor type 1B antibody|Bone morphogenetic protein receptor type IB antibody|Bone morphogenetic protein receptor type-1B antibody|BR 1b antibody|BR1b antibody|CDw 293 antibody|CDw293 antibody| CDw293 antigen antibody|CFK 43a antibody|CFK43a antibody|Serine/threonine receptor kinase antibody|zALK 6 antibody|zALK6 antibody

ID gène: 658

UniProt: O00238