KCNMA1 anticorps (AA 124-467)

N° du produit ABIN3043867

Détail du produit anti-KCNMA1 anticorps

Antigène: KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))

Épitope: AA 124-467

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp KCNMA1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Fonction: Rabbit IgG polyclonal antibody for Calcium-activated potassium channel subunit alpha-1(KCNMA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.

Réactivité croisée (Details): No cross reactivity with other proteins.

Attributs du produit: Rabbit IgG polyclonal antibody for Calcium-activated potassium channel subunit alpha-1(KCNMA1) detection. Tested with WB, IHC-P in Human,Mouse,Rat.
Gene Name: potassium large conductance calcium-activated channel, subfamily M, alpha member 1
Protein Name: Calcium-activated potassium channel subunit alpha-1

Purification: Immunogen affinity purified.

Immunogène: E.coli-derived human KCNMA1 recombinant protein (Position: K124-Q467). Human KCNMA1 shares 99% amino acid (aa) sequence identity with both mouse and rat KCNMA1.

Isotype: IgG

Information d'application

Indications d'application: WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Mouse, Rat, Predicted Species: Human, The detection limit for KCNMA1 is approximately 0.25 ng/lane under reducing conditions.
IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Human, Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.

Commentaires:

Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

Restrictions: For Research Use only

Stockage

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Concentration: 500 μg/mL

Buffer: Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Détails sur KCNMA1

Antigène: KCNMA1 (Potassium Large Conductance Calcium-Activated Channel, Subfamily M, alpha Member 1 (KCNMA1))

Autre désignation: KCNMA1 (KCNMA1 Produits)

Synonymes: anticorps BKTM, anticorps KCa1.1, anticorps MaxiK, anticorps SAKCA, anticorps SLO, anticorps SLO-ALPHA, anticorps SLO1, anticorps bA205K10.1, anticorps mSLO1, anticorps DDBDRAFT_0190653, anticorps DDBDRAFT_0235401, anticorps DDB_0190653, anticorps DDB_0235401, anticorps KCNMA, anticorps KCNMA1, anticorps 5730414M22Rik, anticorps BKCa, anticorps Slo, anticorps Slo1, anticorps mSlo, anticorps mSlo1, anticorps KCNMA1b, anticorps KCNMA1c, anticorps Kcnma, anticorps bktm, anticorps kcnma1-A, anticorps sakca, anticorps cSlo, anticorps slo1, anticorps kcnma1, anticorps si:ch211-39f22.2, anticorps BcDNA:GH10751, anticorps CG10693, anticorps Dmel\CG10693, anticorps Dslo, anticorps dSlo, anticorps dSlo1, anticorps dslo, anticorps fSlo, anticorps potassium calcium-activated channel subfamily M alpha 1, anticorps calcium-activated BK potassium channel, alpha subunit, anticorps potassium large conductance calcium-activated channel, subfamily M, alpha member 1, anticorps potassium calcium-activated channel subfamily M alpha 1 L homeolog, anticorps potassium large conductance calcium-activated channel, subfamily M, alpha member 1a, anticorps calcium-activated potassium channel subunit alpha-1, anticorps slowpoke, anticorps KCNMA1, anticorps kcnma1, anticorps Kcnma1, anticorps kcnma1.L, anticorps kcnma1a, anticorps LOC100454095, anticorps slo

Sujet: Calcium-activated potassium channel subunit alpha-1 also known as KCa1.1, or BK channel for short, is a voltage gated potassium channel encoded by the KCNMA1 gene and characterized by their large conductance of potassium ions (K+) through cell membranes. This gene is located on 10q22.3. BK channels are activated (opened) by changes in membrane electrical potential and/or by increases in concentration of intracellular calcium ion (Ca2+). It is essential for the regulation of several key physiological processes including smooth muscle tone and neuronal excitability. BK channels also contribute to the behavioral effects of ethanol in the worm C. elegans under high concentrations (> 100 mM, or approximately 0.50 % BAC).It remains to be determined if BK channels contribute to intoxication in humans.

Synonyms: subfamily M subunit alpha-1 antibody|bA205K10.1 antibody|BK channel antibody|BKCA alpha antibody|BKCA alpha subunit antibody|BKTM antibody|Calcium activated potassium channel subfamily M subunit alpha 1 antibody|Calcium activated potassium channel subunit alpha 1 antibody|Calcium-activated potassium channel antibody|Calcium-activated potassium channel subunit alpha-1 antibody|DKFZp686K1437 antibody|Drosophila slowpoke like antibody|hSlo antibody|K(VCA)alpha antibody|KCa1.1 antibody|KCMA1_HUMAN antibody|KCNMA 1 antibody|KCNMA antibody|KCNMA1 antibody|Large conductance calcium activated potassium channel subfamily M alpha member 1 antibody|Maxi K antibody|Maxi K channel antibody|Maxi Potassium channel alpha antibody|MaxiK antibody|MGC71881 antibody|OTTHUMP00000060198 antibody|OTTHUMP00000064154 antibody|OTTHUMP00000064155 antibody|OTTHUMP00000064156 antibody|OTTHUMP00000064157 antibody|OTTHUMP00000064158 antibody|OTTHUMP00000064159 antibody|OTTHUMP00000064160 antibody|OTTHUMP00000064161 antibody|OTTHUMP00000064162 antibody|OTTHUMP00000064164 antibody|OTTHUMP00000064165 antibody|Potassium large conductance calcium activated channel subfamily M alpha member 1 antibody|SAKCA antibody|Slo 1 antibody|SLO alpha antibody|SLO antibody|Slo homolog antibody|Slo-alpha antibody|Slo1 antibody|Slowpoke homolog antibody|Stretch activated Kca channel antibody

ID gène: 3778

UniProt: Q12791

Pathways: Regulation of Hormone Metabolic Process, Sensory Perception of Sound