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TJP3 anticorps (C-Term)

TJP3 Reactivité: Rat WB, IHC (p) Hôte: Lapin Polyclonal unconjugated
N° du produit ABIN3044037
  • Antigène Voir toutes TJP3 Anticorps
    TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
    Épitope
    • 10
    • 9
    • 7
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 885-905, C-Term
    Reactivité
    • 32
    • 13
    • 12
    • 2
    Rat
    Hôte
    • 35
    • 2
    Lapin
    Clonalité
    • 36
    • 1
    Polyclonal
    Conjugué
    • 20
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Cet anticorp TJP3 est non-conjugé
    Application
    • 29
    • 17
    • 5
    • 5
    • 3
    • 1
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Fonction
    Rabbit IgG polyclonal antibody for Tight junction protein ZO-3(TJP3) detection. Tested with WB, IHC-P in Mouse,Rat.
    Séquence
    RARDVESSDD EGYDWGPATD L
    Réactivité croisée (Details)
    Predicted Cross Reactivity: mouse
    No cross reactivity with other proteins.
    Predicted Cross Reactivity: Species predicted to be fit for the product based on sequence similarities.
    Attributs du produit
    Rabbit IgG polyclonal antibody for Tight junction protein ZO-3(TJP3) detection. Tested with WB, IHC-P in Mouse,Rat.
    Gene Name: tight junction protein 3
    Protein Name: Tight junction protein ZO-3
    Purification
    Immunogen affinity purified.
    Immunogène
    A synthetic peptide corresponding to a sequence at the C-terminus of mouse Zonula occludens protein 3(885-905aa RARDVESSDDEGYDWGPATDL), identical to the related rat sequence.
    Isotype
    IgG
    Top Product
    Discover our top product TJP3 Anticorps primaire
  • Indications d'application
    WB: Concentration: 0.1-0.5 μg/mL, Tested Species: Rat, Predicted Species: Mouse
    IHC-P: Concentration: 0.5-1 μg/mL, Tested Species: Mouse, Rat, Epitope Retrieval by Heat: Boiling the paraffin sections in 10 mM citrate buffer, pH 6.0, for 20 mins is required for the staining of formalin/paraffin sections.
    Notes: Tested Species: Species with positive results. Predicted Species: Species predicted to be fit for the product based on sequence similarities. Other applications have not been tested. Optimal dilutions should be determined by end users.
    Commentaires

    Antibody can be supported by chemiluminescence kit ABIN921124 in WB, supported by ABIN921231 in IHC(P).

    Restrictions
    For Research Use only
  • Format
    Lyophilized
    Reconstitution
    Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.
    Concentration
    500 μg/mL
    Buffer
    Each vial contains 5 mg BSA, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Thimerosal, 0.05 mg Sodium azide.
    Agent conservateur
    Thimerosal (Merthiolate), Sodium azide
    Précaution d'utilisation
    This product contains Sodium azide and Thimerosal (Merthiolate): POISONOUS AND HAZARDOUS SUBSTANCES which should be handled by trained staff only.
    Conseil sur la manipulation
    Avoid repeated freezing and thawing.
    Stock
    4 °C/-20 °C
    Stockage commentaire
    At -20°C for one year. After reconstitution, at 4°C for one month.
    It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.
    Date de péremption
    12 months
  • Antigène
    TJP3 (Tight Junction Protein 3 (Zona Occludens 3) (TJP3))
    Autre désignation
    TJP3 (TJP3 Produits)
    Synonymes
    anticorps cb766, anticorps wu:fj93c08, anticorps zo-3, anticorps zo3, anticorps ZO-3, anticorps ZO3, anticorps tight junction protein 3, anticorps tight junction protein 3 S homeolog, anticorps tjp3, anticorps tjp3.S, anticorps TJP3, anticorps Tjp3
    Sujet
    TJP3(TIGHT JUNCTION PROTEIN 3), also called ZO3, is a protein that in humans is encoded by the TJP3 gene. TJP3 is a member of the family of membrane-associated guanylate kinase-like proteins(MAGUK) that associate with intracellular junctions(Itoh et al., 1999). Haskins et al.(1998) showed that recombinant Tjp3 binds in vitro translated Tjp1 and binds directly to the cytoplasmic tail of occludin but no binding was detected between Tjp3 and Tjp2. Roh et al.(2002) determined that Tjp3 interacted with PATJ(INADL) and that both proteins colocalized to tight junctions in vivo. In vitro studies showed that the sixth and eighth PDZ domains of PATJ mediated interaction with the Tjp3 C-terminal domain and with Cldn1, respectively.

    Synonyms: Tight junction protein 3 antibody|Tight junction protein ZO-3 antibody|Tight junction protein ZO3 antibody|TJP3 antibody|ZO3 antibody|ZO3_HUMAN antibody|Zona occludens protein 3 antibody|Zonula occludens protein 3 antibody
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