IL-33 anticorps

N° du produit ABIN361077

Détail du produit anti-IL-33 anticorps

Antigène: IL-33 (IL33) (Interleukin 33 (IL33))

Reactivité: Humain

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp IL-33 est non-conjugé

Application: Western Blotting (WB), ELISA

Purification: The antibody was purified from mouse ascitic fluids by protein-G affinity chromatography

Immunogène: Recombinant human IL-33 (112-270aa), Accession / GI number: NP_254274

Clone: 4-00E-09

Isotype: IgG2b kappa

Information d'application

Indications d'application: Recommended dilution 1:500

Restrictions: For Research Use only

Stockage

Format: Liquid

Concentration: 1mg/ml

Buffer: In Phosphate-Buffered Saline (pH7.4) with 0.1% Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Stock: -20 °C

Détails sur IL-33

Antigène: IL-33 (IL33) (Interleukin 33 (IL33))

Autre désignation: IL33 (IL33 Produits)

Synonymes: anticorps IL33, anticorps C9orf26, anticorps DVS27, anticorps IL1F11, anticorps NF-HEV, anticorps NFEHEV, anticorps RP11-575C20.2, anticorps 9230117N10Rik, anticorps Il-33, anticorps Il1f11, anticorps RGD1311155, anticorps interleukin 33, anticorps IL33, anticorps Il33

Sujet: Interleukin 33 (IL-33) is a 32kDa proinflammatory cytokine and intracellular nuclear factor with transcriptional regulatory properties. IL-33 is structurally related to IL-1, which induces helper T cells to produce type 2 cytokines and acts through the receptor IL1RL-1 (IL1 receptor-like-1), which is known also as ST2. Binding of IL-33 to this receptor activates NF-kappa-B and MAP kinases and induces in vitro Th2 cells to produce cytokines. In vivo, IL-33 induces expression of IL-4, IL-5, IL-13 and leads to severe pathological changes in mucosal organs and in vitro, it can be divided to N-terminal fragment of 12kDa and C-terminal fragment of 18kDa by cleavage of caspase-1.Concentration: 1 mg/ml

Pathways: Production of Molecular Mediator of Immune Response