PRKCSH anticorps

N° du produit ABIN317664

Détail du produit anti-PRKCSH anticorps

Antigène: PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PRKCSH est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: This antibody detects endogenous levels of Glucosidase II beta protein.(region surrounding Lys117)

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/10000-1/20000. Western Blot: 1/500-1/1000. Immunofluorescence: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PRKCSH

Antigène: PRKCSH (Protein Kinase C Substrate 80K-H (PRKCSH))

Autre désignation: Glucosidase 2 Subunit beta (PRKCSH Produits)

Synonymes: anticorps AGE-R2, anticorps G19P1, anticorps PCLD, anticorps PKCSH, anticorps PLD1, anticorps 80K-H, anticorps VASAP-60, anticorps zgc:55653, anticorps prkcsh, anticorps MGC75615, anticorps MGC82696, anticorps PRKCSH, anticorps protein kinase C substrate 80K-H, anticorps protein kinase C substrate 80K-H L homeolog, anticorps phospholipase D1, anticorps PRKCSH, anticorps Prkcsh, anticorps prkcsh, anticorps prkcsh.L, anticorps Bm1_42055, anticorps LOC100304710, anticorps LOC100526729, anticorps PLD1

Sujet: Trimming of glucoses from N-linked core glycans on newly synthesized glycoproteins occurs sequentially through the action of Glucosidases I and II in the endoplasmic reticulum (ER). Glucosidase II is an ER-localized enzyme that contains alpha and beta subunits (Glucosidase IIalpha and Glucosidase IIbeta). The alpha and beta subunits form a defined heterodimeric complex with a molecular weight about 161 kDa. Glucosidase IIalpha is the catalyitc core of the enzyme and can function independently of the beta subunit. The sequence of Glucosidase IIbeta encodes protein rich in glutamic and aspartic acid with a putative ER retention signal (HDEL) at the C terminus. The phosphorylated form of Glucosidase IIbeta is localized in the plasma membrane and is highly expressed in FGF stimulated fibroblasts and epidermal carcinoma cells. Glucosidase IIbeta was first purified from a human carcinoma cell line as a potential substrate for protein kinase C. Through the HDEL signal at the C-terminus, Glucosidase IIbeta retains the complete complex in the ER.Synonyms: 80K-H protein, G19P1, Glucosidase II beta, PRKCSH, Protein kinase C substrate 60.1 kDa protein heavy chain

Poids moléculaire: approx. 59 kDa

ID gène: 5589

NCBI Accession: NP_001001329

UniProt: P14314

Pathways: Cellular Glucan Metabolic Process, Methionine Biosynthetic Process