TSC22D1 anticorps

N° du produit ABIN317674

Détail du produit anti-TSC22D1 anticorps

Antigène: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp TSC22D1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of TSC-22 protein.

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/20000-1/40000. Western Blot: 1/500-1/1000. Immunohistochemistry: 1/50-1/200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur TSC22D1

Antigène: TSC22D1 (TSC22 Domain Family, Member 1 (TSC22D1))

Autre désignation: TSC22D1 (TSC22D1 Produits)

Synonymes: anticorps Ptg-2, anticorps TGFB1I4, anticorps TSC22, anticorps AA589566, anticorps AW105905, anticorps Egr5, anticorps TSC-22, anticorps Tgfb1i4, anticorps Tsc, anticorps Tsc22, anticorps tsc22, anticorps TS22A, anticorps fj34d05, anticorps wu:fj34d05, anticorps zgc:65869, anticorps zgc:85857, anticorps TSC22D1, anticorps tsc22d1, anticorps MGC69210, anticorps MGC186361, anticorps DKFZp459J163, anticorps TSC22 domain family member 1, anticorps TSC22 domain family, member 1, anticorps TSC22 domain family member 1 L homeolog, anticorps TSC22D1, anticorps Tsc22d1, anticorps tsc22d1.L, anticorps tsc22d1

Sujet: Transforming growth factor-beta-stimulated clone-22 (TSC-22) acts as a transcriptionalregulator to modulate cell growth and differentiation and cell death. TSC-22 contains a leucine zipper domain as well as a nuclear export signal, resulting in cytoplasmic localization in living cells. However, concomitant with the induction of apoptosis, TSC-22 translocates from the cytoplasm to the nucleus and shows transcriptional regulatory activity. TSC-22 acts as a major downstream component in the TGF-beta pathway, and also the PPARgamma signalling pathway. The association of these two pathways with tumor suppression, and the significant downregulation of TSC-22 mRNA in various cancer types, such as brain and salivary gland tumors, imply an antiproliferative role for TSC-22.Synonyms: Cerebral protein 2, KIAA1994, Regulatory protein TSC-22, TGFB-stimulated clone 22 homolog, TGFB1I4, TSC22, TSC22 domain family protein 1, Transforming growth factor beta-1-induced transcript 4 protein

Poids moléculaire: approx. 16 kDa

ID gène: 8848

NCBI Accession: NP_006013

UniProt: Q15714