MC2R anticorps

N° du produit ABIN317741

Détail du produit anti-MC2R anticorps

Antigène: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp MC2R est non-conjugé

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificité: MC2-R antibody detects endogenous levels of MC2-R protein.(region surrounding Lys289)

Purification: Affinity-chromatography

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur MC2R

Antigène: MC2R (Melanocortin 2 Receptor (Adrenocorticotropic Hormone) (MC2R))

Autre désignation: MC2-R (MC2R Produits)

Synonymes: anticorps ACTHR, anticorps ACTH-R, anticorps MC2-R, anticorps MC2R, anticorps MC2, anticorps melanocortin 2 receptor, anticorps MC2R, anticorps Mc2r, anticorps mc2r

Sujet: The melanocortin family comprises the alpha-, beta- and gamma-melanocyte stimulating hormones (MSH) and adrenocorticotrophin. The receptors for these hormones are seven-transmembrane G protein-coupled proteins that activate adenylyl cyclase. Five melanocortin receptors have been cloned and shown to exhibit different affinities and patterns of expression. MC1-R (MSH-R) is expressed in melanocytes and corticoadrenal tissue. MC2-R is the ACTH receptor and is expressed primarily in the adrenal cortex. MC3-R has been found in specific regions of the brain and is also expressed in placenta and gut. MC4-R is expressed primarily in brain, while MC5-R is expressed at low levels in most tissues examined.Synonyms: ACTH receptor, ACTH-R, ACTHR, Adrenocorticotropic hormone receptor, Adrenocorticotropin receptor, MC2R

ID gène: 4158

NCBI Accession: NP_000520

UniProt: Q01718

Pathways: cAMP Metabolic Process