GALR2 anticorps

N° du produit ABIN317752

Détail du produit anti-GALR2 anticorps

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GALR2 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of GALR2 protein.(region surrounding Ile238)

Purification: Affinity Chromatography using epitope-specific immunogen.

Information d'application

Indications d'application: ELISA: 1/40000approx. 1/60000. Western Blot: 1/500approx. 1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GALR2

Antigène: GALR2 (Galanin Receptor 2 (GALR2))

Autre désignation: GALR2 (GALR2 Produits)

Synonymes: anticorps GALNR2, anticorps mGalR, anticorps GALR2, anticorps GAL2-R, anticorps GALR-2, anticorps galanin receptor 2, anticorps transcription regulator. LacI family, raffinose related, anticorps DNA-binding transcriptional regulator GalR, anticorps galactose operon repressor, anticorps galanin receptor type 2, anticorps GALR2, anticorps Galr2, anticorps LOC100037698, anticorps rafR, anticorps galR2, anticorps LOC103690156

Sujet: Galanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30 amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7 transmembrane family of G protein coupled receptors. GALR2 interacts with the N terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi.Synonyms: GAL2-R, GALNR2, GALR-2, Galanin receptor type 2

Poids moléculaire: approx. 40.0 kDa

ID gène: 8811

NCBI Accession: NP_003848

UniProt: O43603

Pathways: cAMP Metabolic Process, Inositol Metabolic Process, Feeding Behaviour