OPRK1 anticorps

N° du produit ABIN317765

Détail du produit anti-OPRK1 anticorps

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Reactivité: Humain, Rat, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OPRK1 est non-conjugé

Application: Western Blotting (WB)

Specificité: This antibody detects endogenous levels of KOR-1 protein.(region surrounding Arg361)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1/1000-1/5000. Western blot: 1/500-1/1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: PBS, pH ~7.2, 0.05 % Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Références pour anticorps anti-OPRK1 (ABIN317765)

Niwa, Rowbotham, Lambert: "Evaluation of primary opioid receptor antibodies for use in western blotting." dans: British journal of anaesthesia, Vol. 108, Issue 3, pp. 530-2, (2012) (PubMed).

Détails sur OPRK1

Antigène: OPRK1 (Opioid Receptor, kappa 1 (OPRK1))

Autre désignation: kappa Opioid Receptor (OPRK1 Produits)

Synonymes: anticorps OPRK1, anticorps LOC780448, anticorps kor, anticorps KOR, anticorps OPRK, anticorps K-OR-1, anticorps KOR-1, anticorps MSL-1, anticorps Oprk2, anticorps R21, anticorps opioid receptor, kappa 1, anticorps opioid receptor kappa 1, anticorps oprk1, anticorps OPRK1, anticorps Oprk1

Sujet: Opioid is the term used to designate a group of compounds that are opium-like in their properties. These drugs have effects on perception of pain, consciousness, motor control, mood, and autonomic function, and can induce physical dependence. Pharmacological studies suggested that there are at least 3 major classes of opioid receptors, designated delta, kappa, and mu. They differ in their affinity for various opioid ligands and in their cellular distribution. Studies of the receptors in the mouse and rat show that they are structurally related and are members of the family of 7 transmembrane-spanning G protein-coupled receptors. The kappa opiod receptor inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. It is the receptor for beta-endorphin.Synonyms: KOR-1, KOR1, OPRK, OPRK1

Poids moléculaire: approx. 48 kDa

ID gène: 4986

NCBI Accession: NP_000903

UniProt: P41145