Mu Opioid Receptor 1 anticorps

N° du produit ABIN317766

Détail du produit anti-Mu Opioid Receptor 1 anticorps

Antigène: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp Mu Opioid Receptor 1 est non-conjugé

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: This antibody detects endogenous levels of MOR-1 protein.(region surrounding Ser57)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2, 15 mM Sodium Azide

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur Mu Opioid Receptor 1

Antigène: Mu Opioid Receptor 1 (OPRM1) (Opioid Receptor, mu 1 (OPRM1))

Autre désignation: OPRM1 (OPRM1 Produits)

Synonymes: anticorps LMOR, anticorps M-OR-1, anticorps MOP, anticorps MOR, anticorps MOR1, anticorps OPRM, anticorps MOP-R, anticorps MOR-1, anticorps MOR-1O, anticorps Oprm, anticorps mor, anticorps muOR, anticorps MORA, anticorps Oprrm1, anticorps or2, anticorps ZFOR2, anticorps OPRM1, anticorps opioid receptor mu 1, anticorps opioid receptor, mu 1, anticorps outer membrane protein OprM, anticorps OPRM1, anticorps Oprm1, anticorps oprm1, anticorps oprM1

Sujet: Three types of opioid receptors have been cloned: mu, delta, and kappa. Opioid receptors are seven transmembrane G-protein coupled receptors. They share a high degree of homology and are most divergent at the N- and C-termini. Activation of mu opioid receptors leads to a decrease in neuronal excitability. Most actions of exogenous opioids, such as morphine, are mediated through the μ-opioid receptor, including analgesia, tolerance and reward. In general, opioids modulate numerous central and peripheral processes including pain perception, neuroendocrine secretion and the immune response. The opioid signal is transduced from receptors through G proteins to various different effectors. Subsequent to G protein activation, several effectors are known to orchestrate the opioid signal. For example, activation of opioid receptors increases phosphatidylinositol turnover, activates K+ channels and reduces adenylyl cyclase and Ca++ channel activities.Synonyms: MOR1, Mu-type opioid receptor

Poids moléculaire: approx. 48 kDa

ID gène: 4988

NCBI Accession: NP_000905

UniProt: P35372

Pathways: cAMP Metabolic Process, Synaptic Membrane