ELOVL1 anticorps

N° du produit ABIN317834

Détail du produit anti-ELOVL1 anticorps

Antigène: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Reactivité: Humain, Souris

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp ELOVL1 est non-conjugé

Application: Western Blotting (WB)

Specificité: ELOVL1 antibody detects endogenous levels of ELOVL1 protein.(region surrounding Phe139)

Purification: Affinity Chromatography using epitope-specific immunogen

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1.0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH ~7.2 containing 0.05 % Sodium Azide as preservative

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur ELOVL1

Antigène: ELOVL1 (ELOVL Fatty Acid Elongase 1 (ELOVL1))

Autre désignation: ELOVL1 (ELOVL1 Produits)

Synonymes: anticorps AA407424, anticorps BB151133, anticorps Ssc1, anticorps elongation of very long chain fatty acids (FEN1/Elo2, SUR4/Elo3, yeast)-like 1, anticorps ELOVL fatty acid elongase 1, anticorps Elovl1, anticorps ELOVL1

Sujet: Elongation of very long chain fatty acid-like (ELOVL) proteins 1-6 are members of the ELO family of proteins, which play an important role in tissue-specific biosynthesis of very long chain fatty acids and sphingolipids. The ELOVL proteins act as catalysts in fatty acid elongation reduction and localize to the endoplasmic reticulum (ER). Elongation of very long chain fatty acids protein 1 (ELOVL1), also referred to as Ssc1, is the human homolog of the yeast ELO3 protein. It is expressed in a variety of tissues and at especially high levels in stomach, skin, intestine, kidney and lung. ELOVL1 participates in the elongation of very long chain saturated and monounsaturated fatty acids of up to 26 carbons and may be required for the development of a barrier in epithelial cells and skin. ELOVL1 is also important for the formation of Myelin in the central nervous system. Impaired ELOVL1 activity may be associated with disorders of sphingolipid metabolism.Synonyms: 3-keto acyl-CoA synthase ELOVL1, CGI-88, Elongation of very long chain fatty acids protein 1, SSC1

Poids moléculaire: approx. 35 kDa

ID gène: 64834

NCBI Accession: NP_073732

UniProt: Q9BW60