GPRC5A anticorps

N° du produit ABIN317865

Détail du produit anti-GPRC5A anticorps

Antigène: GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))

Reactivité: Humain, Souris, Rat

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp GPRC5A est non-conjugé

Application: Western Blotting (WB)

Specificité: RAI3 antibody detects endogenous levels of RAI3 protein.(region surrounding Leu179)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 15 mM sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur GPRC5A

Antigène: GPRC5A (G Protein-Coupled Receptor, Family C, Group 5, Member A (GPRC5A))

Autre désignation: GPRC5A / RAI3 (GPRC5A Produits)

Synonymes: anticorps GPCR5A, anticorps RAI3, anticorps RAIG1, anticorps Rai3, anticorps Raig1, anticorps G protein-coupled receptor class C group 5 member A, anticorps G protein-coupled receptor, family C, group 5, member A, anticorps G protein-coupled receptor, class C, group 5, member A, anticorps GPRC5A, anticorps Gprc5a

Sujet: Retinoic acid-induced protein 3 (RAI3) is a transmembrane G protein-coupled receptor that affects many essential biological processes including embryogenesis,cell growth, differentiation and apoptosis. RAI3 may also be involved in maintaining homeostasis of epithelial cells. Retinoic acid receptors directly regulate RAI3 during its transcription in embryonal carcinoma differentiation. RAI3 expression is upregulated in most tumor cell lines that express mutant p53, suggesting that p53 interacts with the promoter of RAI3 and represses its expression at the beginning of apoptosis. RAI3 is a potential molecular target for diagnosing breast cancer, selective suppression of signals from RAI3 may have a place in breast cancer treatments.Synonyms: G-protein coupled receptor C5A, GPCR5A, Orphan G-protein-coupling receptor PEIG-1, PEIG-1, RAIG1, Retinoic acid-induced gene 1 protein, Retinoic acid-induced protein 3

Poids moléculaire: approx. 42 kDa

ID gène: 9052

NCBI Accession: NP_003970

UniProt: Q8NFJ5