OXER1 anticorps

N° du produit ABIN317873

Détail du produit anti-OXER1 anticorps

Antigène: OXER1 (Oxoeicosanoid Receptor 1 (OXER1))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp OXER1 est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificité: TG1019 antibody detects endogenous levels of TG1019 protein.(region surrounding Arg251)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur OXER1

Antigène: OXER1 (Oxoeicosanoid Receptor 1 (OXER1))

Autre désignation: Oxoeicosanoid Receptor 1 (OXER1 Produits)

Synonymes: anticorps GPCR, anticorps GPR170, anticorps TG1019, anticorps oxoeicosanoid receptor 1, anticorps OXER1

Sujet: TG1019 is a G protein-coupled receptor that functions as a chemoattractant for eosinophils and neutrophils. TG1019 is expressed in various tissues except the brain, with the highest expression in liver, kidney, peripheral leukocyte, lung and spleen. TG1019 interacts with the protein OXE to form TG1019/OXE, a Gα i/o protein-coupled receptor. Signals from TG1019 are transduced via a Gα i/o protein to PLC/calcium, MEK/ERK and PI3K/Akt pathways. Signal transduction from TG1019 following stimulation with 5-oxo-6E,8Z,11Z,14Z eicosatetraenoic acid (5-oxo-ETE) induces intracellular calcium mobilization and rapid activation of MEK/ERK and PI3K/Akt pathways. TG1019 also may play a role in downregulating cAMP production.Synonyms: 5-oxo-ETE G-protein coupled receptor, GPR170, OXER1, R527, TG1019

Poids moléculaire: approx. 46 kDa

ID gène: 165140

NCBI Accession: NP_683765

UniProt: Q8TDS5

Pathways: cAMP Metabolic Process