PTGDR anticorps

N° du produit ABIN317875

Détail du produit anti-PTGDR anticorps

Antigène: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Reactivité: Humain

Hôte: Lapin

Clonalité: Polyclonal

Conjugué: Cet anticorp PTGDR est non-conjugé

Application: Western Blotting (WB), Immunofluorescence (IF)

Specificité: PD2R antibody detects endogenous levels of PD2R protein.(region surrounding Glu301)

Purification: Affinity chromatography

Information d'application

Indications d'application: ELISA: 1: 40000approx. 1: 60000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Stockage

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS) with 0.05 % sodium azide, approx. pH 7.2.

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freezing and thawing.

Stock: 4 °C/-20 °C

Stockage commentaire: Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.

Détails sur PTGDR

Antigène: PTGDR (Prostaglandin D2 Receptor (PTGDR))

Autre désignation: PTGDR (PTGDR Produits)

Synonymes: anticorps AS1, anticorps ASRT1, anticorps DP, anticorps DP1, anticorps PTGDR1, anticorps Ptgdr, anticorps Ptgdr2, anticorps PTGDR, anticorps PGD, anticorps prostaglandin D2 receptor, anticorps prostaglandin D receptor, anticorps PTGDR, anticorps Ptgdrl, anticorps Ptgdr

Sujet: The prostaglandin D2 receptor is a member of the G-protein-coupled receptor (GPCR) family (subfamily: prostanoid). It has been shown to function as a prostanoid DP receptor. Its activity is mainly mediated by G-S proteins that stimulate adenylate cyclase resulting in an elevation of intracellular cAMP and Ca2+. Knockout studies in mice suggest that the ligand of this receptor, prostaglandin D2 (PGD2), functions as a mast cell-derived mediator to trigger asthmatic responses. Prostaglandin D2 receptor has been reported to be expressed in human small intestine, colon (goblet cells), eye, and eosinophils. ESTs have been isolated from human brain libraries.Synonyms: ASRT1, PGD receptor, PGD2 receptor, Prostaglandin D2 receptor, Prostanoid DP receptor

Poids moléculaire: approx. 40 kDa

ID gène: 5729

NCBI Accession: NP_000944

UniProt: Q13258

Pathways: Thromboxane A2 Receptor Signaling